Stress & Anxiety

Stress is the normal day-to-day pressure and tension we have from our daily lives. Time limits, money, delays, remembering to pick up the kids and many other daily events can become stressful when taken together and repeated day-in day-out. A certain amount is normal, even healthy. But in excess or when poorly dealt with, it can lead to Anxiety.

Anxiety is manifested with a sense of excess worry, unease and nervousness. It is usually associated with an upcoming event (such as a wedding) or something with an uncertain outcome (such as an exam result).

As with Depression, Anxiety is a normal response when proportionate to the situation. Everyone will experience both of these reactions at some point in their life. However, when the reaction is overwhelming or continues for an extended period of time, it is pathological. Anxiety without a real cause or when disproportionate to the situation is also not normal and requires treatment.

Anxiety can be associated with a number of physical symptoms, such as fast heart rate, palpitations, sweating, breathlessness, panic attacks, insomnia, headache and migraines, fatigue, pre-menstrual symptoms etc.

The medical causes of Anxiety disorders is not fully understood. However, life experiences and inherited traits may both be related.

There are a number of types of Anxiety disorder recognised today:
1. Agorophobia
2. Panic disorder
3. Social Phobia
4. Specific Phobias (reaction to a specific factor), etc.

Anxiety can be related to a number of other medical disorders:
1. Heart disease
2. Hyperthyroidism
3. Asthma, COPD
4. Chronic pain
5. Recreational drug use
6. Withdrawal from recreational drugs, alcohol or anti-anxiety medication
7. Side effect of certain medications.

In Traditional Medicine, Anxiety disorders can have several causes:
1. Qi Stagnation
2. Phlegm or Damp Obstruction
3. Melancholy
4. Deficiency
5. Unsettled Spirit

Western Tradition

TCM Classification

Simples:
Camomile
Borage
Lemon Balm
Valerian
Rose
Cannabis
Passionflower
Amber

Hops
Violet
St. Johns Wort
Cyperus rotundus
Sandalwood
Kava
Convolvulus microphyllus

Platycladus, Bai Zi Ren
Polygala, Yuan Zhi
Panax, Ginseng
Ziziphus, Suan Zao Ren
Salvia Dan Shen
Bupleurum Chai Hu
Combinations:
Balm & St. Johns wort
Betony & Vervain
Motherwort & Cyperus
Lavender & Rosemary
Hops, Balm, Valerian
Rose, Sandalwood & Licorice

Platycladus Bai Zi Ren & Zizyphus Suan Zao Ren
Bupleurum Chai Hu & Paeonia Bai Shao


Differential Diagnosis:

Wind / Qi Stagnation:
Qi stagnation or Wind manifests with feeling of tension or distention in the back, shoulders or torso. The mind will be overactive, thinks and moves a lot, fidgeting etc; the Pulse will be wiry or jumping, tongue is typically dry and may be elongated.
Tincture of Balm
Powder of Happiness (Letificans)
Syrup of Mugwort
Aloeswood 35 (Tibetan Medicine)
Sarasvata Churna (Ayurveda)

Xiao Yao San
Dan Zhi Xiao Yan San
Mu Xiang Liu Qi Yin
1. Paeonia Bai Shao, Curcuma Yu Jin, Calamus (Shi Chang Pu), Cyperus rotundus (Xiang Fu)


Phlegm and Damp Obstructing:
Phlegm and Damp obstructs the Mind and clouds the reasoning and judgement. There is often a ‘foggy’ feeling, a heavy feeling in the body, pulse is low or obstructed, tongue will have a thick or greasy tongue coat and may be elongated.
Aromatic Pills of Aloes
Hiera Logadi
Pills to Clarify
Sarasvata Churna (Ayurveda)
Ling Gui Zhu Gan Tang
Ban Xia Hou Po Tang
An Shen Ding Zhi Wan
Gun Tan Wan

1. Atractylodes Bai Zhu, Curcuma Yu Jin, Calamus (Shi Chang Pu), Poria Fu Ling


Heart Deficiency:
Confusion, Insomnia, sleeps lightly, palpitations with Anxiety, feeling of weakness; Pulse is weak or slightly irregular, Tongue may be dry and may have a red tip.
Royal Confection of Kermes (Mesue)
Exhilarative Syrup (Laurent)
Cordial Decoction
Aromaticum rosatum
Cooling Exhilarating Electuary (Unani)
Letificans Cooling Electuary (Unani)

Gui Pi Tang–Heart and Spleen Deficiency
Tian Wang Bu Xin Wan–Heart Yin Deficiency
Ding Zhi Wan–Heart weakness with Damp
Huang Lian E Jiao Tang–Yin deficient Heat
Suan Zao Ren Tang–Heart Blood & Yin Deficiency

1. Salvia Dan Shen, Dang Gui, Zizyphus semen Suan Zao Ren, Polygala Yuan Zhi
2. Rose, Sandalwood, Saffron, Pearl


Qi and Blood Deficiency
When the Qi and Blood are weak it is easier to become stressed or anxious or depressed, partly because day-to-day life can be overwhelming when run down. The face will be pale, the pulse low along with Fatigue.
Royal Confection of Kermes (Mesue)
Ba Zhen Tang
Gui Pi Tang
Ding Zhi Wan

1. Ginseng, Dang Gui, Schisandra Wu Wei Zi, Cyperus rotundus (Xiang Fu)


Melancholy
Anxiety and Fear without cause; a sense of doom, desire for solitude, inability to face day-to-day life; there is a dull complexion, deep and weak or faint pulse and a darkness of the eyes.
Powder of Happiness (Letificans)
Powder for Melancholy (Philon)
Pills of Lapis Lazuli
Pills to Clarify


Restless Mind and Spirit
Cooling Pearl Powder (Diamargariton Frigidum)
Cooling Powder of Gems
Tian Wan Bu Xin Dan
Suan Zao Ren Tang
Zhu Sha An Shen Wan
An Shen Ding Zhi Wan
Zhen Zhu Mu Wan

General Formula:

Infusion of Seven Flowers
Cordial Decoction
Syrup of Mugwort
Exhilarative Syrup (Laurent)
Tincture of Balm
Tincture of St. John’s wort
Tincture of Valerian
Powder to Strengthen the Head
Powder of Happiness (Letificans)
Electuary for Sadness and Worry

Aloeswood 31 (Tibetan Medicine)
Aloeswood 35 (Tibetan Medicine)
Mental Happiness (Sems kyi bde skyid) (Tibetan)
Sarasvata Churna (Ayurveda)

Liver Qi Stagnationm
Anxiety, irritability, restlessness, hypochondriac distention, headache, irregular menstruation, PMS
Xiao Yao San
Dan Zhi Xiao Yan San (with Heat)
Ban Xia Hou Po Tang (with feeling of lump in throat)


Heart and Spleen Deficiency
Anxiety, forgetful, palpitations, insomnia, withdrawal, poor appetite, pale complexion, pale tongue, weak pulse.
Gui Pi Tang


Heart Blood and Yin Deficiency
Anxiety, irritability, palpitation, poor memory, insomnia, red tongue with a little coat, rapid and thin pulse. 
Tian Wang Bu Xin Wan
Yang Xin Tang
Zhen Zhu Mu Wan


Research:

General
Herbal medicines in the treatment of psychiatric disorders: 10-year updated review.
Herbal Medicine for Anxiety, Depression and Insomnia.
Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence.
Clinical applications of herbal medicines for anxiety and insomnia; targeting patients with bipolar disorder.
Effects of traditionally used anxiolytic botanicals on enzymes of the gamma-aminobutyric acid (GABA) system.
Comparative evaluation of Melissa officinalis L., Tilia europaea L., Passiflora edulis Sims. and Hypericum perforatum L. in the elevated plus maze anxiety test
Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review
Herbal Medicine for Depression and Anxiety: A Systematic Review with Assessment of Potential Psycho-Oncologic Relevance

Withania:
An alternative treatment for anxiety: a systematic review of human trial results reported for the Ayurvedic herb ashwagandha (Withania somnifera).
An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study
Body Weight Management in Adults Under Chronic Stress Through Treatment With Ashwagandha Root Extract: A Double-Blind, Randomized, Placebo-Controlled Trial.
Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study

Balm
Pilot trial of Melissa officinalis L. leaf extract in the treatment of volunteers suffering from mild-to-moderate anxiety disorders and sleep disturbances.
Effects of Herbal combination (Melissa officinalis L. and Nepeta menthoides Boiss. & Buhse) on insomnia severity, anxiety and depression in insomniacs: Randomized placebo controlled trial.
Melissa officinalis L. hydro-alcoholic extract inhibits anxiety and depression through prevention of central oxidative stress and apoptosis.
The effects of Melissa officinalis supplementation on depression, anxiety, stress, and sleep disorder in patients with chronic stable angina.
Anti-stress effects of lemon balm-containing foods.
Anxiolytic effects of a combination of Melissa officinalis and Valeriana officinalis during laboratory induced stress.
Anxiolytic and antidepressant-like effects of Melissa officinalis (lemon balm) extract in rats: Influence of administration and gender.
Effects of chronic administration of Melissa officinalis L. extract on anxiety-like reactivity and on circadian and exploratory activities in mice.

Other Herbs:
The anxiolytic effects of a Valerian extract is based on Valerenic acid
[Kava-kava preparations–alternative anxiolytics].
Cannabinoids in clinical practice.
Effects of Rosmarinus officinalis L. on memory performance, anxiety, depression, and sleep quality in university students: A randomized clinical trial.
The effects of alcoholic extract of saffron (Crocus satious L.) on mild to moderate comorbid depression-anxiety, sleep quality, and life satisfaction in type 2 diabetes mellitus: A double-blind, randomized and placebo-controlled clinical trial.
Methanol extract of semen Ziziphi Spinosae attenuates ethanol withdrawal anxiety by improving neuropeptide signaling in the central amygdala.