Sida, Bala

Indian Country Mallow
Bala (Ayurveda)
Bala, Beej Band (Unani)
Xin Yin Huang Hua Zai (TCM)
Picture Sida cordifolia
Martius, Eichler, Urban, Flora Brasiliensis, 1891

Picture Sida cordifolia
(Photo by Karen Pagel) (Wikimedia)

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Botanical name:


Sida cordifolia (syn. Malva tormentosa)

Parts used:


Root (rarely the seed or fresh plant juice)

Temperature & Taste:


Cool, moist. Sweet

Uses:


1. Strengthens the Kidneys, Nourishes Yin:
-gives strength, weight-increasing, nourishing; weakness, fatigue, emaciation, convalescence
-increases sexual potency, nourishes Sperm, regarded as Aphrodisiac (root, seed)
spermatorrhoea, nocturnal pollution, premature ejaculation, and to increase the viscosity of semen (seed, Unani)
-polyuria, urinary frequency

2. Clears Heat and Damp, Resists Poison:
-Urinary infection, blood in the urine
-Diarrhea, Dysentery
-Damp-Heat Jaundice (TCM)

3. Clears Heat, Resists Poison:
-Intermittent Fever with cold chills and shivering, followed by stronger heat and Fever
-heat-type Cough; Asthma
-Gonorrhea; Sexually Transmitted Disease

4. Nourishes Yin, Settles Wind:
-Neuralgia, Sciatica, Paralysis, Facial Paralysis
-Arrhythmia, Tachycardia, Irregular Pulse, Palpitations
-also for Mental Illness

5. Clears Heat, Stops Bleeding:
-Bleeding (decoct with milk)
-Excessive Menstrual Bleeding (powder with Honey)

6. Externally:
-external preparations (mostly oils) for arthritis, paralysis, hemiplegia, rheumatism and Vata/Wind diseases.


Dose:


Powder: 500mg–3 grams (5 grams daily);

Comment:


… available in PRO version

Substitutes:


… available in PRO version

Main Combinations:


Frequently combined with Abutilon Atibala in classical Ayurvedic texts.

1. Rejuvenate and regulates Wind constitutions:
i. Sida cordifolia, … available in PRO version
ii. Sida cordifolia with … available in PRO version
iii. Sida cordifolia, … available in PRO version
2. Urinary frequency or urgency from Heat:
i. Sida cordifolia powder … available in PRO version
ii. Sida cordifolia with … available in PRO version
3. Diarrhea, Sida … available in PRO version
4. Fever:
i. Intermittent Fever, Sida cordifolia … available in PRO version
ii. Sida cordifolia with … available in PRO version
iii. Chronic Fever, Edema, Anemia, Sida cordifolia with … available in PRO version
5. Asthma, Wheezing:
i. Sida cordifolia with … available in PRO version
ii. Sida cordifolia with … available in PRO version
6. Bronchitis with Fever, Sida cordifolia with … available in PRO version
7. Impotence, Sida cordifolia with … available in PRO version
8. Infertility:
i. Sida cordifolia with … available in PRO version
ii. Sida cordifolia with … available in PRO version
9. Paralysis, Facial Paralysis, Parkinsonism:
i. Sida cordifolia with … available in PRO version
ii. to the preceding can be added … available in PRO version
iii. Facial Paralysis and Sciatica, Sida cordifolia … available in PRO version
iv. Parkinson’s, Sida cordifolia, … available in PRO version
10. Heart disease:
i. Sida cordifolia with … available in PRO version
i. Sida cordifolia with … available in PRO version
11. Mental disorders:
i. Sida cordifolia with … available in PRO version
ii. Sida cordifolia with … available in PRO version
12. Goiter, Sida cordifolia with … available in PRO version

Cautions:


1. Not used in Phlegm conditions
2. Hypertension
3. Contains Ephedrine (less than 10% of that found in Ephedra).
4. It has been banned in some countries (including the U.S.) due to the Ephedrine content.

Toxicity:


The extract showed low acute toxicity.
Anti-inflammatory, analgesic activity and acute toxicity of Sida cordifolia L. (Malva-branca).

Drug Interactions:


Due to Ephedrine content, full doses may interact with:
1. Caffeine and MAO inhibitors, increasing blood pressure
2. Beta-Blockers (reduces efficacy due to opposing action)
3. Ephedrine medication (such as Sudafed), causing ephedrine toxicity, arrhythmia etc.
4. Steroids (dexamethasone), enhancing clearance thereby reducing effectiveness.

Main Preparations used:




The plants belonging to this genus are known in Sanskrit by the general name Bala. Four kinds are mentioned in medical works, namely, Batyalaka (S. cordifolia), Mahabala (2. var of S. rhombifolia), Nagabala (S. spinosa). The Hindus regard the roots of the different species of Sida as cooling, astringent and tonic; they prescribe them in nervous and urinary diseases, and in fever. The root bark is beaten up with milk and sugar, and aromatics and stimulants arc sometimes added. (For original prescriptions, see Dutt’s “Hindu Materia Medica, p.121.) In the Concan the leaves of S. cordifolia (Chikana) with other cooling leaves are applied in ophthalmia; the root-juice is used to promote the healing of wounds, and the juice of the whole plant pounded with a little water is given
 in 1/4 seer doses for spermatorrhoea. The root of S. carpinifolia (Tupkaria) is applied with sparrow’s dung to burst boils. The Mahometans consider Bala to be aphrodisiac. Ainslie notices several species of Sida, and the uses to which they are applied by the Hindus. The authors of the Bengal Dispensatory, after a trial of the roots of Sida carpinifolia, were unable to satisfy themselves as to its febrifuge action, but it was found to promote perspiration, to increase the appetite, and to act as a useful bitter tonic. In Goa the Portuguese value it as a diuretic, especially in rheumatic affections; they also use it as a demulcent in gonorrhoea’. (Vegetable Materia Medica of Western India, Dymock, 1885)
ANTI-INFLAMMATORY
Anti-Inflammatory Effect of Malva sylvestris, Sida cordifolia, and Pelargonium graveolens Is Related to Inhibition of Prostanoid Production.
Analgesic, antiinflammatory and hypoglycaemic activities of Sida cordifolia
Anti-inflammatory, analgesic activity and acute toxicity of Sida cordifolia L. (Malva-branca).
Anti-inflammatory and analgesic alkaloid from Sida cordifolia linn
Anti-inflammatory and antioxidant effect of Kerabala: a value-added ayurvedic formulation from virgin coconut oil inhibits pathogenesis in adjuvant-induced arthritis.

ANTI-PYRETIC:
Preliminary evaluation of anti-pyretic and anti-ulcerogenic activities of Sida cordifolia methanolic extract.

ANTI-OXIDANT:
Ameliorative effect of Sida cordifolia in rotenone induced oxidative stress model of Parkinson’s disease.
Nrf2-mediated antioxidant response by ethanolic extract of Sida cordifolia provides protection against alcohol-induced oxidative stress in liver by upregulation of glutathione metabolism.
Antiperoxidative and antiinflammatory effect of Sida cordifolia Linn. on quinolinic acid induced neurotoxicity.
Role of Sida cordifolia L. leaves on biochemical and antioxidant profile during myocardial injury.
Free radical scavenging capacity, anticandicidal effect of bioactive compounds from Sida cordifolia L., in combination with nystatin and clotrimazole and their effect on specific immune response in rats
Anti-inflammatory and antioxidant effect of Kerabala: a value-added ayurvedic formulation from virgin coconut oil inhibits pathogenesis in adjuvant-induced arthritis.
Screening of antioxidant activity of three Indian medicinal plants, traditionally used for the management of neurodegenerative diseases.

ANALGESIC:
Toxicity assessment and analgesic activity investigation of aqueous acetone extracts of Sida acuta Burn f . and Sida cordifolia L. (Malvaceae), medicinal plants of Burkina Faso.
Analgesic, antiinflammatory and hypoglycaemic activities of Sida cordifolia
Anti-inflammatory, analgesic activity and acute toxicity of Sida cordifolia L. (Malva-branca).
Anti-inflammatory and analgesic alkaloid from Sida cordifolia linn

ANTI-STRESS, ADAPTOGENIC:
Antistress, Adoptogenic Activity of Sida cordifolia Roots in Mice
CNS DEPRESSANT ACTIVITY:
CNS pharmacological effects of the hydroalcoholic extract of Sida cordifolia L. leaves.

NEUROPROTECTIVE:
Antiperoxidative and antiinflammatory effect of Sida cordifolia Linn. on quinolinic acid induced neurotoxicity.

NEURODEGENERATIVE DISEASE / PARKINSON’S DISEASE:
Ameliorative effect of Sida cordifolia in rotenone induced oxidative stress model of Parkinson’s disease.
Association of L-DOPA with recovery following Ayurveda medication in Parkinson’s disease.
Screening of antioxidant activity of three Indian medicinal plants, traditionally used for the management of neurodegenerative diseases.

HYPOTENSIVE:
Cardiovascular effects of Sida cordifolia leaves extract in rats.

VASORELAXANT EFFECT:
Endothelium-derived factors and k+ channels are involved in the vasorelaxation induced by Sida cordifolia L. in the rat superior mesenteric artery.

HYPOGLYCEMIC:
Analgesic, antiinflammatory and hypoglycaemic activities of Sida cordifolia

HEPATOPROTECTIVE:
Amelioration of alcohol-induced hepatotoxicity by the administration of ethanolic extract of Sida cordifolia Linn.

LIVER REGENERATIVE EFFECT:
Effect of the aqueous extract of Sida cordifolia on liver regeneration after partial hepatectomy

ARTHRITIS:
New herbal composition (OA-F2) protects cartilage degeneration in a rat model of collagenase induced osteoarthritis.
Anti-inflammatory and antioxidant effect of Kerabala: a value-added ayurvedic formulation from virgin coconut oil inhibits pathogenesis in adjuvant-induced arthritis.

ANTI-ULCER:
Preliminary evaluation of anti-pyretic and anti-ulcerogenic activities of Sida cordifolia methanolic extract.

WOUND HEALING ACTIVITY:
Wound healing activity of Sida cordifolia Linn. in rats
Sida cordifolia accelerates wound healing process delayed by dexamethasone in rats: Effect on ROS and probable mechanism of action