Pinellia, Ban Xia 半夏

Prepared Pinellia, Zhi Ban Xia 制半夏

Ban Xia (TCM)
Picture Pinellia ternata
Blume, Rumphia, 1835

Picture Picture
Left: Lime-prepared Pinellia   Right: Ginger-prepared Pinellia (Jiang Ban Xia) (Adam, 2017)
Picture Prepared Pinellia Fa Ban Xia as commonly used in the West (Adam, 2017)

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Botanical name:


Pinellia ternata

Parts used:


Prepared Rhizome

Temperature & Taste:


Very Warm, dry. Pungent. Toxic

Classification:


P. Clear Cold Phlegm

Uses:


1. Dries Damp, Clears Cold-Phlegm:
-Cough with copious sputum; Thick white sputum
-Phlegm or Damp associated with Spleen deficiency
-main medicine for Phlegm and Damp diseases in TCM

2. Stops Vomiting and Nausea, Directs Qi Downward:
-Nausea and Vomiting from excess Phlegm and rising Stomach Qi
-can be used for any type of Nausea and Vomiting depending on the medicines its combined with
focal distention in the chest and epigastrium

3. Clears Phlegm, Reduces Masses:
-Phlegm-type Scrofula, Nodes and Kernels in the skin

Dose:


… available in PRO version

Preparation:


… available in PRO version
Picture

Main Combinations:


1. Cold-Phlegm and Damp diseases:
i. Pinellia Ban Xia with … available in PRO version
ii. with Spleen and Qi deficiency, Pinellia Ban Xia with … available in PRO version
2. Internal Damp with external Wind-Cold (inc. indigestion, acute gastroenteritis, food poisoning, traveller’s diarrhea) combine Pinellia Ban Xia with … available in PRO version
3. Phlegm-Heat of the Lungs with Coughing of yellow sputum:
i. Pinellia Ban Xia with … available in PRO version
ii. Pinellia Ban Xia with … available in PRO version
4. Wind-Cold Cough or Wheezing, Pinellia Ban Xia with … available in PRO version
5. Asthma:
i. Pinellia Ban Xia, … available in PRO version
ii. Pinellia Ban Xia, … available in PRO version
6. Phlegm and Qi obstruction with feeling of obstruction in the Throat, Pinellia Ban Xia with … available in PRO version
7. Nausea and Vomiting:
i. Cold-Phlegm with Nausea, Vomiting, combine Pinellia Ban Xia with … available in PRO version
ii. from Stomach Heat, Pinellia Ban Xia with … available in PRO version
iii. from Damp-Cold, Pinellia Ban Xia with … available in PRO version
8. Severe Nausea and Vomiting during pregnancy, Pinellia Ban Xia with … available in PRO version
9. Spleen Qi deficiency with Phlegm and Damp:
i. Pinellia Ban Xia, … available in PRO version
ii. with more severe Cold and Qi stagnation, add … available in PRO version
10. Food Stagnation with Phlegm, Pinellia Ban Xia, … available in PRO version
11. Wind-Phlegm Dizziness and Vertigo, Pinellia Ban Xia with … available in PRO version
12. Phlegm masses, Scrofula, Lymphadenitis, Pinellia Ban Xia, … available in PRO version
13. Chills and Fever with sore throat, nausea, or Malarial Fever, Pinellia Ban Xia with … available in PRO version
14. Cholecystitis, Pinellia Ban Xia, … available in PRO version

Major Formulas:


Er Chen Tang
Xiao Chai Hu Tang
Da Chai Hu Tang
Ban Xia Hou Po Tang
Xiao Qing Long Tang
Ban Xia Bai Zhu Tian Ma Tang
Liu Jun Zi Tang
Xiang Sha Liu Jun Zi Tang
Bao He Wan
Ding Chuan Tang
Hai Zao Yu Hu Tang
Huo Xiang Zheng Qi Shui

Cautions:


1. Very drying. Not suitable for Yin deficiency
2. Not suitable for Dry Cough and Coughing Blood
3. Only the prepared rhizome should be used internally.

Toxicity:


1. Toxicity is primarily due to Calcium Oxalate crystals and Lectins.
2. A 4 week repeated-dose toxicity study in rats with water extracts of Pinellia Ban Xia at doses up to 2000mg/kg/day showed no ill effects (see here)
3. 6 gm/kg/day of Pinellia Ban Xia for 10 days given to rats showed changes in phospholipid metabolism, amino acid metabolism and carnitine metabolism. No Liver or Kidney toxicity was noted. (see here)

Antidotes:
1. A strong decoction of fresh Ginger can be taken to neutralize the toxicity in case of overdose.
2. Alum solution is used in the preparation of Pinellia Ban Xia and has been shown to attenuate toxicity.

Drug Interactions:


Not used with Aconitum species.

Main Preparations used:



GENERAL / REVIEW
The ethnobotanical, phytochemical and pharmacological profile of the genus Pinellia
Pinellia ternata (Thunb.) Breit: a review of its germplasm resources, genetic diversity and active components
Study on chemical constituents in rhizome of Pinellia ternata
A comprehensive review on ethnopharmacological, phytochemical, pharmacological and toxicological evaluation, and quality control of Pinellia ternata (Thunb.) Breit.

ANTIBACTERIAL
Pinelloside, an antimicrobial cerebroside from Pinellia ternata
Pinellia ternata agglutinin expression in chloroplasts confers broad spectrum resistance against aphid, whitefly, Lepidopteran insects, bacterial and viral pathogens

ANTI-VIRAL
Pinellia ternata agglutinin expression in chloroplasts confers broad spectrum resistance against aphid, whitefly, Lepidopteran insects, bacterial and viral pathogens

IMMUNOSTIMULATING
Characterization of an acidic polysaccharide with immunological activities from the tuber of Pinellia ternata

ASTHMA
Network pharmacology-based study on the mechanism of pinellia ternata in asthma treatment

COPD:
Pinellia ternata Attenuates Mucus Secretion and Airway Inflammation after Inhaled Corticosteroid Withdrawal in COPD Rats

ANTI-EMETIC:
An anti-emetic principle of Pinellia ternata tuber
REFLUX ESOPHAGITIS / GASTRO-ESOPHAGEAL REFLUX:
A comparative study on the effects of Pinellia ternata, zingiber officinale and sobanhatang on reflux esophagitis
Efficacy and safety of modified Banxia Xiexin decoction (Pinellia decoction for draining the heart) for gastroesophageal reflux disease in adults

ANTI-OBESITY:
Anti-obesity effect of Pinellia ternata extract in Zucker rats

HYPERTENSION:
Network Pharmacology and Molecular Docking Combined to Analyze the Molecular and Pharmacological Mechanism of Pinellia ternata in the Treatment of Hypertension

INSOMNIA
Pinellia ternata (Thunb.) Makino Preparation promotes sleep by increasing REM sleep

ANTI-DEPRESSANT:
Exploring the potential antidepressant mechanisms of pinellia by using the network pharmacology and molecular docking

EHRLICH ASCITES TUMOR:
Study on anti-ehrlich ascites tumor effect of Pinellia Ternata polysaccharide in vivo.

ANTI-CANCER:
Structural characterization of an acid polysaccharide from Pinellia ternata and its induction effect on apoptosis of Hep G2 cells
Purification of a mannose-binding lectin Pinellia ternata agglutinin and its induction of apoptosis in Bel-7404 cells
A polysaccharide from Pinellia ternata inhibits cell proliferation and metastasis in human cholangiocarcinoma cells