Persica, Peach tree, Tao Ren 桃仁

Tao Ren (Peach kernel, TCM)
Klung kham  ཀླུང་ཁམ་ (Tibet)
Picture
Picture Ortus Sanitatis, Meydenbach, 1491

Picture Dioscorides Materia Medica, Mathias, 1563

Picture Icones Plantarum Medcio-oeconomico, Vietz, 1806


Botanical name:


Prunus persica

Parts used:


Kernels; Flowers; Leaf; Fruit
The twigs were occasionally used the same as the Leaves in the West.

Temperature & Taste:


Kernel: Neutral in TCM (slightly Warm in the West); Moist. Bitter, Sweet
Leaf, Flower: Warm, dry.
Fruit: Cool, moist

Classifications:


2A APERIENT
3D. CORDIALS & CARDIACS.   3E. DIURETIC.    3F. LITHONTRIPTIC.    3G. EMMENAGOGUE.   3Q. ANTHELMINTIC
4e. STOMACHIC.    4h. NEPHRITIC

Uses:


PEACH KERNEL:
1. Moves the Blood, Clears Stasis (TCM, West):
-menstrual disorders with fixed pain and dark or clotted Blood
-Postpartum Pain
-Tumors, Fibroids, Abdominal masses
-Lung and Intestinal abscess
-Trauma, Bruising
-also for Leukorrhea

2. Promote Urine, Breaks Stones:
-Gravel and Stones (West)
-regarded as very useful for Stones, both to pass and relieve pain

3. Moves the Bowels (TCM, West):
-open Obstruction of the Liver: Jaundice
-used for abdominal pain
-clears Heat of the Stomach

-gentle moist laxative laxative

4. Relieves Cough and Asthma:
-Cough, Wheezing and Asthma (used like Almond)

5. Kills Worms:
-commonly used in Europe to kill and expel Worms

6. Externally:
-externally used in Emulsions against Headaches

-kernels bruised and boiled in vinegar until it is thick, is applied to bald places to promote hair growth. (Culpeper)
-in Tibet to promote growth of hair (oil or decoction topically)

NOTE:
Peach kernel is an important herb to treat Blood Stagnation in TCM. It is also used in TCM as a laxative for Constipation from dryness and weakness. In Europe, it was used for Blood stasis including Apoplexy and Tumors, and was also commonly used for Stones and to Kill Worms.


PEACH LEAF & BARK:
1. Clears Liver Heat:
-Liver congestion; Jaundice; Chronic Hepatitis (Scudder)
-checks vomiting, and stops nausea including morning sickness.
-gentle, mild purgative (esp as a Syrup)
-Stomach, Bowel and Liver conditions associated with heat.
-bark of the Peach tree was said to be the best remedy for Jaundice (Vitalogy)

2. Promotes Urine, Clears Heat and Damp:
-scalding, painful urine
-Hematuria.

3. Clears Phlegm, Stops Cough and Wheezing:
-Cough, chronic Bronchitis, Wheezing, Whooping cough

4. Moves the Blood:
-amenorrhea and abdominal masses and tumors.
-Palpitations.

5. Clears Wind-Heat, Resists Poison:
-Folk Remedy for Fever and Influenza (some commended the infusion)
-the fresh leaves applied to prevent Tetanus (reportedly effective even once lock-jaw begins)

6. Kills worms:
-boiled in milk and taken, or a plaster of the leaves laid to the navel of young children was used to kill Worms

7. Externally:
-used in douches for Uterine prolapse, Vaginal Trichomoniasis
-the leaf and been beaten and applied to Cervical Cancer in TCM.


PEACH TREE FLOWER:
1. Kills Worms:
-Worms in children

2. Moves the Bowels:
-loosen the Belly, opens obstruction of the Mesentery, purges Water



PEACH TREE RESIN:
1. Used for hoarseness, loss of voice, and other defects of the Lungs, including spitting of blood.
2. Considered specific for Stones. (Usually used with Honey)
3. Used as a substitute for Gum Arabic


Dose:


KERNELS: often 15–20 are taken as a dose (for adults)
KERNELS in DECOCTION: 3–6 grams, up to 9 grams (to be taken in 3 equal doses);
LEAF in DECOCTION: 3–6 grams; or half an ounce may be infused in 500 mls of boiling water and taken in Tablespoon doses
BARK in DECOCTION: 3–9 grams
TINCTURE of the BARK (1:5 in 45%): 2–15 drops in water, 2–3 times daily;
PEACH TREE RESIN: 2–6 grams;

Substitute:


1. Bitter Almonds have similar opening, blood-moving effects to Peach kernel, and were also used similarly for Stones. They are regarded as stronger and were more commonly used than Peach kernels in the west.

Main Combinations:


Peach kernel / Bitter Almond kernel & Saffron / Safflower

KERNEL:
1. Usually combined with Safflower (or Saffron) in TCM. Together, these activate the Blood and clear Blood Stasis.
2. Postpartum pain, Peach kernel with Comfrey, Nutmeg and Amber
3. Apoplexy, Loss of Speech, prepare an emulsion of Peach kernels with Pennyroyal water
4. To purge stagnant Blood and Heat (symptoms include headache, vertigo, tinnitus, palpitations, constipation) Peach kernel with Rhubarb, Cinnamon twig and Licorice (as in Tao He Cheng Qi Tang)
5. Amenorrhea, Peach kernel with Dang Gui and Safflower
6. Leukorrhea, Peach kernels tinctured in brandy.
7. Jaundice, beat Peach kernels with vinegar, enough to make it like thin broth. Take this on an empty stomach. (Brunschwig, 1561)
8. Lung Cancer, Peach kernel, Rhubarb, Paeonia Mu Dan Pi
9. Dysuria, Peach kernel, Medlar kernel (equal parts), powder, add sugar (equal to the rest) and take with white wine. (The Secrets of Alexis, 1615)
10. Stones:
i. make an Electuary of Peach kernel with Raisins
ii. take 18 or 20 Peach kernels with quarter ounce of Raisins and drink Pea broth after (Wirtzung)
iii. Urinary stones were treated with Sparganium San Len, Zedoary (E Zhu), Peach kernel (Tao Ren), Paeonia Chi Shao (and others). 100 cases were given the formula every 3 days, 74 were cured, 14 benefited.
11. Worms:
i. Peach kernels, Wormwood
ii. Peach kernels, Pumpkin seed
iii. Peach kernels with Citron seed, Purslane seed and Wormseed

LEAF:
1. Bright’s Disease, Peach leaf with equal parts of Queen of the Meadow (Vitalogy)
2. Uterine prolapse, Peach leaf with Soloman’s Seal, Hops as a douche (Vitalogy)
3. Gastritis, use a fomentation of Peach leaf and Hops made in vinegar and water, while taking an infusion of Peach leaves internally in tablespoonful doses every hour. (Vitalogy).

FLOWER:
1. Worms in Children, Seville Orange seed taken with Syrup of Peach flowers

RESIN:
1. Cough, shortness of Breath, take Peach tree resin a decoction of Coltsfoot.
2. Stones, Peach tree resin with Lemon or Radish juice. (Culpeper)

Major Formulas


Powder for After-pains

Bu Yang Huan Wu Tang
Da Huang Mu Dan Tang
Da Huang Zhe Chong Wan
Di Dang Tang
Gui Zhi Fu Ling Wan
Run Chang Wan
Shen Tong Zhu Yu Tang
Sheng Hua Tang
Tao He Cheng Qi Tang
Tao Hong Si Wu Tang
Xue Fu Zhu Yu Tang

Cautions:


KERNEL:
1. Not used during Pregnancy.
2. Avoid overdose of the kernel; overdose can be fatal.

Toxicity of the Kernel:
7-10 pieces can be fatal to children; 50–60 pieces for adults. This is due to hydrolysis of amygdalin which results in small amounts of hydrocyanic acid which inhibits the respiratory center. Symptoms of overdose include difficulty breathing, spasms, dilated pupils; serious cases may cause coma and death.

Drug Interactions


1. Hydrocyanic acid may potentiate the respiratory depressant effect of Morphine.

Main Preparations used:


Preserved Fruit, Water of the Flowers, Diuretic Water of the Kernels, Syrup of Peach Flowers, Conserve of Peach Flowers, Expressed Oil of Peach Kernels

GENERAL / REVIEW
Toxicity and clinical reasonable application of Taoren (Semen Persi-cae) based on ancient and modern literature research

COMBINATIONS
Taoren Honghua Drug Attenuates Atherosclerosis and Plays an Anti-Inflammatory Role in ApoE Knock-Out Mice and RAW264.7 Cells.
Taoren-Honghua herb pair and its main components promoting blood circulation through influencing on hemorheology, plasma coagulation and platelet aggregation.
Taoren-dahuang herb pair reduces eicosanoid metabolite shifts by regulating ADORA2A degradation activity in ischaemia/reperfusion injury rats.
A multicenter, randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of Taoren Honghua Jian granule in patients with stable coronary artery disease.

ANTIBACTERIAL
–(leaf) Cytotoxic, antimicrobial and nitric oxide inhibitory activities of supercritical carbon dioxide extracted Prunus persica leaves.

ANTI-INFLAMMATORY
Anti‑inflammatory role of Prunus persica L. Batsch methanol extract on lipopolysaccharide‑stimulated glial cells.

ANTIOXIDANT
Multiple protective effect of peptides released from Olea europaea and Prunus persica seeds against oxidative damage and cancer cell proliferation.

ANTI-ALLERGY
Anti-allergic inflammatory effects of cyanogenic and phenolic glycosides from the seed of Prunus persica.
–(fruit) Anti-allergic inflammatory activity of the fruit of Prunus persica: role of calcium and NF-kappaB.

PROMOTES CIRCULATION
Taoren-Honghua herb pair and its main components promoting blood circulation through influencing on hemorheology, plasma coagulation and platelet aggregation.

SUBDURAL HEMATOMA
Nonsurgical treatment of chronic subdural hematoma with Chinese herbal medicine: A STROBE-compliant retrospective study.

VASORELAXANT
–(branch) Endothelium-Dependent Vasorelaxant Effect of Prunus Persica Branch on Isolated Rat Thoracic Aorta.

ATHEROSCLEROSIS
Taoren Honghua Drug Attenuates Atherosclerosis and Plays an Anti-Inflammatory Role in ApoE Knock-Out Mice and RAW264.7 Cells.

HEART DISEASE
A multicenter, randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of Taoren Honghua Jian granule in patients with stable coronary artery disease.
HEPATOPROTECTIVE
Phytochemical Screening and Protective Effects of Prunus persica Seeds Extract on Carbon Tetrachloride-Induced Hepatic Injury in Rats.
The Effects of Taoren-Honghua Herb Pair on Pathological Microvessel and Angiogenesis-Associated Signaling Pathway in Mice Model of CCl4-Induced Chronic Liver Disease.

LIVER FIBROSIS
Pharmacokinetics and anti-liver fibrosis characteristics of amygdalin: Key role of the deglycosylated metabolite prunasin.

NICOTINE TOXICITY
–(fruit) Protective Effect of White-fleshed Peach (Prunus persica (L.) Batsch) on Chronic Nicotine-induced Toxicity.

OBESITY (flowers)
Anti-Obesity Effects of a Prunus persica and Nelumbo nucifera Mixture in Mice Fed a High-Fat Diet.
Anti-Obesity Effects of the Flower of Prunus persica in High-Fat Diet-Induced Obese Mice.

CANCER
Anti-tumor promoting effect of glycosides from Prunus persica seeds.
Multiple protective effect of peptides released from Olea europaea and Prunus persica seeds against oxidative damage and cancer cell proliferation.
Apoptosis induction of Persicae Semen extract in human promyelocytic leukemia (HL-60) cells.
-(leaf) Cytotoxic, antimicrobial and nitric oxide inhibitory activities of supercritical carbon dioxide extracted Prunus persica leaves.
–(root) Ethanol Extract of Root of Prunus persica Inhibited the Growth of Liver Cancer Cell HepG2 by Inducing Cell Cycle Arrest and Migration Suppression.
–(fruit) Polyphenolics from peach (Prunus persica var. Rich Lady) inhibit tumor growth and metastasis of MDA-MB-435 breast cancer cells in vivo.

SYNERGISTIC WITH CHEMOTHERAPY
–(fruit) Extract of Prunus persica flesh (PPFE) improves chemotherapeutic efficacy and protects against nephrotoxicity in cisplatin-treated mice.

PROTECTS AGAINST CHEMOTHERAPY TOXICITY
–(fruit) Extract of Prunus persica flesh (PPFE) improves chemotherapeutic efficacy and protects against nephrotoxicity in cisplatin-treated mice.
–(fruit) The pericarp extract of Prunus persica attenuates chemotherapy-induced acute nephrotoxicity and hepatotoxicity in mice.
–(fruit) The extract of Prunus persica flesh (PPFE) attenuates chemotherapy-induced hepatotoxicity in mice.

UV SKIN DAMAGE (flowers)
The extract of the flowers of Prunus persica, a new cosmetic ingredient, protects against solar ultraviolet-induced skin damage in vivo.
Protection against ultraviolet B- and C-induced DNA damage and skin carcinogenesis by the flowers of Prunus persica extract.
Protection of the flowers of Prunus persica extract from ultraviolet B-induced damage of normal human keratinocytes.