Parkinson’s Disease
Classically called Shaking PalsyParkinson’s Disease is a progressive degenerative disease of the Nervous system. There may be spasms, tremors, rigidity, and loss of motor control. It is most common in middle- and old-age. It is caused by degeneration of basal ganglia and dopamine deficiency.
In Traditional Medicine is an age-related disease associated with Yin and Essence deficiency. Depending on symptoms, it can also be classified as a Wind disease, usually being Wind associated with Yin deficiency. Either Phlegm/Damp (moist) or Melancholy (dry).
Ayurvedic research suggests herbs with cleansing therapies (Panchkarma) work more effectively than herbs alone. Oleation of the body is particularly important in Vata (Wind) diseases.
A number of herbs have demonstrated beneficial effects against Parkinson’s: Mucuna, Wild Rue, Cannabis
Related Diseases
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by relentless loss of motor neuron function, usually resulting in death within 2–5 years. Its diagnosis and treatment overlaps Parkinson’s Disease from a Traditional Medicine perspective. Di Huang Yin Zi has proved very effective in some cases (see a case history of a 12 year survivor here)
Herbs most commonly used for Parkinson’s Disease in TCM (See review here and here)
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Paeonia Bai Shao Ligusticum Chuan Xiong Angelica Dang Gui Polygonum He Shou Wu |
Calamus (Shi Chang Pu) Coptis Huang Lian Gastrodia Tian Ma Uncaria Gou Teng |
Cornus Shan Zhu Yu Codonopsis Dang Shen Licorice Scorpion |
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Walnut Turmeric Safflower Gastrodia Tian Ma Cuscuta seed Tu Si Zi |
Scutellaria Huang Qin Pueraria Ge Gen Lycium Gou Qi Paeonia Bai Shao |
Syrian Rue (Peganum Mucuna Gynostemma Ginkgo |
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Western Tradition Simples
Warming Pearl Powder (Diamargariton Calidum) (Avic.) Warming Pearl Powder (Diamargariton Calidum) (Mes.) Electuary of Pearl (Actuarius) Rhododendron 18 (Dwa lis bco brgyad) Rinchen Ratna Samphel (Precious Wish Fulfilling Jewel) Supreme 25 (Bla med nyer lnga) |
Chinese Classification Simples
Liver Excess, Spleen Deficiency Yi Guan Jian Internal Wind Tian Ma Gou Teng Yin Zhi Jing San Ding Xian Wan Blood Stagnation Tong Qiao Huo Xue Tang Phlegm Obstruction with Wind Ban Xia Bai Zhu Ban Xia Tang Ban Xia Hou To Tang Blood Deficiency with Internal Wind Bu Gan Tang E Jiao Ji Zi Huang Tang San Jia Fu Mai Tang Qi and Yin Deficiency Sheng Mai San Yin deficiency with Rising Liver Yang Da Ding Feng Zhu Tian Ma Gou Teng Yin Yin and Yang Deficiency with Phlegm Obstruction Di Huang Yin Zi (see below) Essence Deficiency Dizziness, Tinnitus, Lower Back pain, early greying, senility Zuo Gui Wan |
Special Formula
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Di Huang Yin Zi Rehmannia Shu Di Huang 15 grams Cornus Shan Zhu Yu 15 grams Cistanches Rou Cong Rong 15 grams Morinda Ba Ji Tian 15 grams Aconitum Fu Zi 15 grams Cinnamom (Rou Gui) 15 grams Dendrobium Shi Hu 15 grams Ophiopogon Mai Men Dong 15 grams Schisandra Wu Wei Zi 15 grams Calamus (Shi Chang Pu) 15 grams Polygala Yuan Zhi 15 grams Poria Fu Ling 15 grams Mint (Bo He) 6 grams Prepared as a decoction with fresh Ginger and Chinese Dates (Da Zao). This is a standard treatment for diseases such as Aphasia, Paralysis and Parkinson’s Disease. Modified version of Di Huang Yin Zi Rehmanniae Shu Di Huang 15 grams Cornus Shan Zhu Yu 12 grams Cistanches Rou Cong Rong 15 grams Epimedium Yin Yang huo 15 grams Aconitum Fu Zi 6 grams Ophiopogon Mai Men Dong 15 grams Anemarrhena Zhi Mu 15 grams Caklamus (Shi Chang Pu) 6 grams Polygala Yuan Zhi 6 grams Trichosanthes seed Gua Lou Ren 30 grams Scorpion (Quan Xie) 6 grams Pit Viper (Agkistrodon Qi She) 9 grams This formula has been used for Amyotrophic lateral sclerosis (ALS). One case having used it for 12 years (see here) Yin Xie Ling Zedoary 3 parts Licorice 2 parts Dark plum fruit 5 parts Lithospermum Zi Cao 2 parts Paeonia Bai Shao 3 parts Sarcandra 5 parts China root (Tu Fu Ling) 5 parts This was demonstrated to be Neuroprotective and effective in animal models of Parkinson’s disease. (See research here) Parkinson’s Formula Mistletoe Sang Ji Sheng Oyster shell (Mu Li). 20 grams ea. Rehmannia Shu Di Huang Rehmannia Sheng Di Huang Peony (Bai Shao) Abalone (Shi Jue Ming) 15 grams ea. Cornus Shan Zhu Yu. Gastrodia Tian Ma Achyranthes Niu Xi Angelica Dang Gui 9 grams ea. Licorice 6 grams This has been designed specifically for Parkinson’s Disease. It is for the pattern of Yin deficiency with rising Liver Yang. Parkinson’s Formula Mistletoe Sang Ji Sheng Salvia Dan Shen Hematite (Dai Zhe Shi) Abalone shell (Shi Jue Ming) Peony (Bai Shao) Melia Chuan Lian Zi Cyperus Xiang Fu Gastrodia Tian Ma Uncaria Gou Teng Achyranthes Niu Xi Dang Gui Peach kernel(Tao Ren) Safflower (Hong Hua) Curcuma Yu Jin Calamus (Shi Chang Pu) Olibanum (Ru Xiang) Myrrh (Mo Yao) Licorice This is used for Blood and Qi stagnation with Liver weakness. |
AyurvedIc combination Henbane seed Mucuna Withania Sida cordifolia Modern Chinese Combination (1) Paeonia Mu Dan Pi Bupleurum Chai Hu Angelica dahurica Bai Zhi This is a modern combination that has been studied. Modern Chinese Combination (2) Rehmannia Shu Di Huang Cistanche Rou Cong Rong Achyranthes Niu Xi Cornus Shan Zhu Yu This is a modern combination that has been studied. Kyung Ok Ko (Korean Medicine) Rehmannia Shu Di Huang Lycium Gou Qi Zi Aloeswood (Chen Xiang) Poria Fu Ling Ginseng Honey This has been studied in a Parkinson’s disease model Cong Rong Shu Jing Cistanche Rou Cong Rong Polygonatum Yu Zhu Salvia Dan Shen Paeonia Rubra Chi Shao Yao Paeonia Mu Dan Pi This has been studied. DA-9805 Paeonia Mu Dan Pi Angelica dahurica Bai Zhi Bupleurum Chai Hu This combination has been studied and found effective to restore motor dysfunction (see here) |
Research:
GENERAL / REVIEW–Important medicinal herbs in Parkinson’s disease
–Effects of Five Ayurvedic Herbs on Locomotor Behaviour in a Drosophila melanogaster Parkinson’s Disease Model
–Association of L-DOPA with recovery following Ayurveda medication in Parkinson’s disease.
–Chinese Herbal Products for Non-Motor Symptoms of Parkinson’s Disease in Taiwan: A Population-Based Study
FORMULAS
–Bushen-Yizhi Formula Alleviates Neuroinflammation via Inhibiting NLRP3 Inflammasome Activation in a Mouse Model of Parkinson’s Disease.
–Dihuang Yinzi, a Classical Chinese Herbal Prescription, for Amyotrophic Lateral Sclerosis: A 12-Year Follow-up Case Report
–Tianma Gouteng Yin, a Traditional Chinese Medicine decoction, exerts neuroprotective effects in animal and cellular models of Parkinson’s disease