Nardostachys, Indian Spikenard

Nardi Indica, Nard
Jatamansi, Mansi (Ayurveda)
Cadamancil (Siddha)
Sumbul-e-Hindi, Sambul-ut-Teeb, Balchhar (Unani)
Gan Song 甘松 (TCM)
Spang spos  སྤང་སྤོས་ (Tibet)
Picture
Picture Herbarius latinus, Petri, 1485

Picture Ortus Sanitatis, Meydenbach, 1491

Picture Picture
Indian Spikenard
De Materia Medica
, Dioscorides, 1555

Indian Spikenard
Krauterbuch, Danz & Uffenbach
, 1610

Picture Various types of Spikenard, including Indian and Celtic Spikenard
Museum Museorum, Valentini, 1704

Picture Indian Spikenard
Curtis’s Botanical Magazine, vol. 107 (1881)

Picture Nardostachys jatamansi (Adam, 2024)

BUY INDIAN SPIKENARD POWDER
Picture

Botanical name:


Nardostachys jatamansi (syn. N. grandiflora)
In the Chinese Pharmacopoeia, N. chinensis, as well as N. jatamansi is listed as the source of Gan Song.
‘there is a false Spikenard of Narbo, and a mountain Spikenard like Valerian’. (Schroder)

Parts used:


Root (Rhizome)

Temperature & Taste:


Slightly Warm (Cool according to some sources), dry. Sweet, Pungent, Aromatic
Nard is Hot in the First and Dry in the Second degree”. (Avicenna)
Warm in TCM, Cool in Tibetan Medicine

Classifications:


2A APERIENT.   2H. CARMINATIVE.    2I. ANTISPASMODIC.    2S. STRENGTHENING
3C. ALEXIPHARMIC.    3G. EMMENAGOGUE.    3J. INCREASE SEMEN
4c. CARDIAC.    4i. UTERINE.    4j. NERVINE
TCM:
J. Regulate Qi

Uses:


1. Regulates Qi, Settles Wind, Clears Phlegm:
-Epilepsy, Hysteria, Convulsions, Palpitations, Hypertension.
-opens the orifices of the brain to improve consciousness and clear the senses
-disturbed Mental state and Insomnia (API)
-excessive worrying that has damaged the Spleen (Chen & Chen)
-regarded as rejuvenative for the Brain; “Strengthens the brain” (Avicenna)
-“All kinds of Nard are useful in Palpitation”. (Avicenna)

2. Moves the Qi, opens Obstructions:
-Colic, Bloating, Gastrointestinal spasms and pain
-good for the Stomach, poor appetite, nausea; used for ‘corrosions’ of the Stomach
Epigastric and abdominal distension with anorexia and vomiting (Chinese Pharmacopoeia)
-sudden onset epigastric and abdominal pain and distention (Ben Cao Gang Mu)

-promotes Urine; also for Jaundice
-Liver Qi obstruction; Jaundice

-aromatically revives the senses when blocked by Phlegm and Damp
-“Nard removes the obstructions of the Liver and Stomach and strengthens them”. (Avicenna)

3. Moves Qi, Regulates Menstruation:
-painful or obstructed Menstruation
-“Stops excessive Bleeding from the Uterus”. (Avicenna)
-“Useful in all kinds of Uteritis. For this purpose the patient is given a sitz bath in its decoction”. (Avicenna)
  
4. Clears Wind-Damp, Resists Poison:
-skin diseases including Erysipelas (API)
-Toxicity associated with Heat (Tibet)
    
5. Externally:
-in hair oils to stop Loss of hair and for premature greying of Hair.
-Freckles, Acne, Black spots (Ben Cao Gang Mu)
-Gargle for Toothache and Caries (Ben Cao Gang Mu, Chinese Pharmacopoeia)
-Swollen legs and feet; can be used as a wash

-externally in Lixiviums for the head and baths for the Womb
-as a collyrium applied with an eye pencil it promotes growth of eyelashes
(Avicenna)
-Hemorrhoids (Ben Cao Gang Mu)


Dose:


Decoction: 3–6 grams
Powder: 500mg–3 grams (up to 5 grams)
Tincture (1:4 in 50% alcohol): 1–5 mls.
Essential Oil: 1–3 drops, three times daily

Substitute:


1. Valerian and Indian Spikenard have been used as substitutes for one another.
2. Celtic Spikenard is also used similarly, but is weaker.
3. Selinum tenuifolium is used as a substitute in the Himalayas.

Correctives:


1. Tabasheer corrects the harmful effects (Unani)
2. It is enhanced with Atractylodes Cang Zhu and Aconitum Fu Zi. (Ben Cao Gang Mu)

Main Combinations:


Wind / Nervous / Brain:
1. Nervous disorders:
i. Indian Spikenard with Centella, Convolvulus Shakhapushpi
ii. Indian Spikenard with Withania and Bacopa
2. Insomnia:
i. Indian Spikenard, Camomile, Balm
ii. Indian Spikenard with Rose, Pearl, Red Coral
3. Epilepsy, Convulsions:
i. in Children,
Indian Spikenard, Peony root, Mistletoe, Pearl
ii. Indian Spikenard with Withania, Centella, Calamus, Henbane seed
4. To enhance cognition and learning:

i. Indian Spikenard with Withania and Bacopa
ii. Indian Spikenard with Peony, Sage, Balm
5. Parkinson’s Disease:

i. Indian Spikenard, Peony, Mistletoe, Sage, Rosemary
ii. Indian Spikenard, Peony, Calamus, Frankincense, Pearl, Red Coral
iii.
Indian Spikenard with Withania, Mucuna, Henbane seed, Sida cordifolia
6. Forgetfulness, Amnesia:
i. Indian Spikenard, Calamus, Frankincense
ii. Indian Spikenard, Calamus, Cyperus rotundus, Withania
iii. Indian Spikenard with Black Pepper, Long Pepper, Galangal, Calamus, Saffron, Asarabacca
7. Depression:
i. Indian Spikenard, Balm, Licorice
ii. Indian Spikenard, St. John’s wort, Lavender
iii. Indian Spikenard (8 parts), Withania (4 parts), Henbane seed (1 part). This is an Ayurvedic compound called Mamsyadi Kwatha and has proven Antipressant effects)
8. Excessive worry causing Spleen deficiency, Indian Spikenard with Amomum Sha Ren, Atractylodes Bai Zhu

Liver, Qi Stagnation:
9. Liver Obstruction and Jaundice:
i. Indian Spikenard, Wormwood
ii. Indian Spikenard, Wormwood, Rose, Quince juice (as in Syrup of Wormwood)
iii. Indian Spikenard with Bitter Almond, Aniseed, Wormwood (as in Troches for the Liver and Jaundice)
iv. Indian Spikenard with Myrrh, Cassia Wood, Saffron, Costus, Cinnamon (as in Electuary of Saffron Lesser of Mesue)
v. Jaundice, Complex Fever, Chronic disease, Indian Spikenard with Rose, Rhubarb, Licorice, Tabasheer, Agrimony (as in Troches of Rose and Agrimony of Mesue)
vi. with Liver Heat, Indian Spikenard with Rose, Sandalwood, Wormwood, Tabasheer, Chicory
10. Qi stangation in the Chest and Abdomen:
i. Indian Spikenard, Costus, Calamus, Aniseed
ii. Indian Spikenard, Sandalwood, Greater Cardamon, Mastic
iii. Indian Spikenard, Costus (Mu Xiang), Citrus Chen Pi (TCM)
iv. with Cold, Indian Spikenard with Ginger, Clove
11. Hardness of the Liver and Spleen, Indian Spikenard, Saffron, Long Birthwort, Ammoniac, Costus (Syrian ‘Book of Medicine‘, Budge, 1913)
12. Obstruction and Pain of the Liver, Spleen, Stomach, Kidneys, Jaundice, and chronic Cough, Spikenard, Costus, Cinnamon, Pepper, Rock Parsley seed, Calamus, Orris, Raisins (Syrian ‘Book of Medicine‘, Budge, 1913)
13. To purge Bile and Liver Heat, Indian Spikenard with Rhubarb and Mastic (as in Powder of Rhubarb of Fuchs)

Digestion:
14. Stomach weakness:
i. Indian Spikenard with Amomum Sha Ren, Citrus Chen Pi, Licorice
ii. Indian Spikenard with Greater Cardamon, Costus, Mastic
iii. Indian Spikenard with Wormwood, Rose, Wine Quince (as in Syrup of Wormwood)
15. Colic, Stomach discomfort:
i. Indian Spikenard, Fennel, Costus
ii. Indian Spikenard with Cardamon, Ginger, Licorice
16. Spleen Dampness, Indian Spikenard with Cinnamon, Rose, Sandalwood, Nutmeg, Greater Cardamon, Mastic (as in Indian Electuary Greater of Mesue)
17. Abdominal discomfort and pain with cold and Qi stagnation, Indian Spikenard, Costus, Amomum Sha Ren (TCM)
18. Gastric Ulcer:
i. Indian Spikenard, Mastic, Rose
ii. Indian Spikenard, Aloe, Mastic
iii. Indian Spikenard, Licorice, Rose (see research here)

Cough / Catarrh:
19. Catarrh, Indian Spikenard with Myrrh and Storax
20. Spasmodic Cough, Indian Spikenard with Elecampane, Adhatoda
21. Qi stagnation in the chest with Cough and fullness, Indian Spikenard, Citrus Chen Pi

Urinary:
22. Urinary Incontinence, Indian Spikenard with Cyperus, French Lavender, Frankincense bark, Acorn cups, Cumin Powder for Incontinence)
23. Edema, Urinary obstruction:
i. Indian Spikenard with Agaric, Cardamon, Costus, Rhubarb, Cinnamon (as in Pills of Spikenard)
ii. Indian Spikenard with Cinnamon, Asarum, Mastic, Fennel, Wormwood, Rhubarb, Parsley (as in Antidote for Edema of Nicholas)
iii. Indian Spikenard, Cinnamon, Clove

Heart:
24. Palpitations, Arrhythmias:
i. Indian Spikenard, Arjuna
ii. Indian Spikenard, Arjuna, Boerhaavia, Sida cordifolia (Ayurveda)
iii. Indian Spikenard, Salvia Dan Shen, Cinnamon, Sandalwood (TCM)
vi. Indian Spikenard with Mastic, Aloeswood, Cinnamon (as in Aloeswood Powder for Palpitations)
v. Indian Spikenard with Aloeswood, Rose, Mastic, Cinnamon, Clove, Nutmeg (as in Troches of Aloeswood)
vi. Indian Spikenard with Mastic, Aloeswood, Cinnamon, Clove, Nutmeg, Cardamon, Citron peel, Musk
vii. Indian Spikenard, Isatis Folium Da Qing Ye, Codonopsis Dang Shen, Ginseng, Cinnamon twig (Gui Zhi), Bitter Orange (Zhi Ke), Licorice. This was used in a clinical trial with an effectiveness of 83%. (Chen & Chen)
viii. Indian Spikenard, Codonopsis Dang Shen, Notoginseng San Qi, Polygonatum Huang Jing, Amber (this formula has been studied for effectiveness)
25. Angina Pectoris:
i. Indian Spikenard, Arjuna, Nutmeg
ii. Indian Spikenard, Olibanum, Saffron, Camphor

Gynecology / Obstetrics:
26. Dysmenorrhea:
i. Indian Spikenard with Cinnamon, Saffron
ii. Indian Spikenard with Peony root, Myrrh, Fennel seed
iii. Indian Spikenard, Cyperus rotundus, Asparagus racemosus, Bishop’s Weed seed
27. Dysmenorrhea, Muscle pain or Headache from Qi and Blood stagnation:
i. Indian Spikenard with Bdellium and Ginger (Ayurveda)
ii. Indian Spikenard with Cyperus rotundus
, Ligusticum Chuan Xiong (TCM)
28. Infertility from Uterus obstruction:
i. Indian Spikenard with Aloe, Agaric, Myrrh, Madder, Cinnamon, Saffron
ii. Indian Spikenard with Peony root, Cinnamon, Cyperus, Mugwort, Clove, Olibanum, Mastic
29. Difficult Childbirth:
i. Indian Spikenard with Cinnamon, Saffron
ii. Indian Spikenard with Savin, Marjoram, Lavender

Other:
30. Cold-Damp Arthritis, Rheumatism, Back Pain, Indian Spikenard with Aloe, Gum Ammoniac, Myrrh, Rue, Dodder herb, Cinnamon, Saffron
31. Watering Eyes, Indian Spikenard with Cinnamon, Mastic, Agaric (as in Electuary for Watering of the Eyes of Andrezeos)
32. Toothache from Kidney deficiency, Indian Spikenard, Sulphur (equal parts). Powder and soak in hot water and rinse the mouth with it. (Jing Xiao Ji Shi Fang)

Major Formulas


Decoction for Difficult Childbirth (Barbette)
Syrup of Wormwood
Tincture Against Schirrus of the Spleen
Hiera Picra
Warming Pearl Powder (Diamargariton Calidum) (Mesue)
Powder to Ascertain if Pregnant (Gabelhover)
Troches of Agrimony
Troches of Aloeswood (Trochisci Aquilaria) (Mesue)
Troches of Rose Lesser (Mesue)
Troches of Rose and Agrimony (Mesue)
Troches of Nutmeg (Rhasis)
Troches of Gallia Sebellinae (Mesue)
Troches for the Liver and Jaundice (Nicholas)
Antidotum Immortale
Antidotum Augustini (Nicholas)
Antidotum Epilepticus (Nicholas)
Athanasia Minor Nicholas
Athanasia Greater Nicholas
Christian Electuary (Unani)
Confection for Catarrh
Diacameron Minus (Nicholas)
Diacameron Magna (Diathamaron) (Nicholas)
Electuarium Acharistum (Nicholas)
Electuary Against Forgetfulness
Electuary for Back Pain (Galen)
Electuary for Pregnancy (Unani)
Electuary for Sadness and Worry
Electuary for Watering of the Eyes of Andrezeos
Electuary of Aloeswood (Unani)
Electuary of Gentian (Unani)
Electuary of Saffron Lesser (Diacrocon Minus) (Mesue)
Electuary of Roman Spikenard
Electuary of Indian leaf (Zenon)
Indian Electuary Greater (Mesue)
Triphera of the Saracens (Triphera Saracenica Magna)
Foetid Pills (Mesue)
Magisterial Imperial Pills
Pills of Spikenard
Pills Proven for Vision (Galen)
Pills to Clarify Pilulae Lucis Majores Mesue

Chebula 7 (A ru bdun pa) (Tibetan) 
Nutmeg Powder (Jatiphaladi Churna) (Ayurveda)
Sarpagandha Ghana Vati (Ayurveda)
Supreme 25 (Bla med nyer lnga) (Tibetan)
Universal Conquering Vajra (Tibetan)

Cautions:


Generally Safe and well tolerated.
1. Caution in Qi deficiency (use with Qi tonics)
2. Use cautiously in Yin deficient Heat or Heat in the Blood.

Toxicity:


Oral LD50 of the isolated sesquiterpene valeranone was reported to be greater than 3160 mg/kg in rats and mice

Main Preparations used:


Oil of Spike (made by boiling in water, wine and oil), and a Compound Oil

Click the Tabs above for more information on this Medicin
This plant, in Sanskrit Jatamansi, has from a very remote period been in use among the Hindus as a perfume and medicine. It is mentioned by Susruta, and is prescribed by Hindu physicians as a nervine tonic and aromatic adjunct in the preparation of medicinal oils and ghritas (butters). In the Pharmacopoeia of India it is stated that Jatamansi enters into the composition of a nostrum, highly recommended in the treatment of epilepsy by Susruta. Dutt, in his Hindu Materia Medica (p. 180), says:— “I do not find in Susruta’s work any prescription for epilepsy, containing Jatamansi, except the following, in which, however, it can hardly be said to be an active ingredient. Take of the pulse of Phaseolus Roxburghii, barley, jujube fruit, seeds of Crotalaria juncea, bdellium, jatamansi root, the ten drugs collectively called dasamula, and chebulic myrobalans equal parts, and prepare a decoction in the usual manner. This decoction is recommended to be administered with the addition of clarified butter and goat’s urine. Arabic and Persian writers describe Jatamansi under the name of Sumbul aud Sumbul-i-Hindi, the latter term being used to distinguish it from Valerian, which is sometimes called Sumbul. The author of the Makhzan-el-Adwiya says that it is the Nardin of the Greeks (Dioscorides, I.6), and compares the root to the tail of a sable. He considers it to be deobstruent and stimulant, diuretic and
emmenagogue, and recommends it in various disorders of the digestive and respiratory organs, and as a nervine tonic in hysteria, He also notices the popular opinion that it promotes the growth and blackness of the hair. Jatamansi in doses of 45 grains is often employed as an expectorant in coughs and colds.

Ainslie notices that the Vytians in Lower India prepare a fragrant and cooling liniment for the head from this drug, and also prescribe it internally as a purifier of the blood. Sir W. Jones thought that the Spikenard ointment of the ancients might have been made from N. Jatamansi. (Asiat. Res. II. p. 405, and IV., p. 109.) However this may be, there can be no doubt that Jatamansi has been used in India for a similar purpose from a very early date, and that. the principal use of the drug at the present time, is for making hair washes and ointments. Sir W. O’Shaughnessy states, as the result of his experience with Jatamansi, that it is a prefect representative for Valerian. (Bengal Disp., p. 404.) It is very desirable that further trials should be instituted with this promising drug, which can be procured, at a small cost, in almost all the bazars throughout India. Care should be taken to select good specimens for trial, as the central portion of the root is often destroyed by insects. (Vegetable Materia Medica of Western India, Dymock, 1885
GENERAL / REVIEW
A review on traditional uses, phytochemistry, pharmacology, toxicology and the analytical methods of the genus Nardostachys.

COMPARISON WITH VALERIAN
A comparative clinical study on the effect of Tagara (Valeriana wallichii DC.) and Jatamansi (Nardostachys jatamansi DC.) in the management of Anidra (primary insomnia)
Comparative and Functional Screening of Three Species Traditionally used as Antidepressants: Valeriana officinalis L., Valeriana jatamansi Jones ex Roxb. and Nardostachys jatamansi (D.Don) DC.

ANTIOXIDANT
Antioxidant, Biomolecule Oxidation Protective Activities of Nardostachys jatamansi DC and Its Phytochemical Analysis by RP-HPLC and GC-MS
In Vitro Screening for Anti-Cholinesterase and Antioxidant Activity of Methanolic Extracts of Ayurvedic Medicinal Plants Used for Cognitive Disorders
Standardization and in vitro antioxidant activity of jatamansi rhizome

ANTI-INFLAMMATORY
Beneficial Effects of Fractions of Nardostachys jatamansi on Lipopolysaccharide-Induced Inflammatory Response

ANTI-NEUROINFLAMMATORY
Chemical Analysis of the Ingredients of 20% Aqueous Ethanol Extract of Nardostachys jatamansi through Phytochemical Study and Evaluation of Anti-Neuroinflammatory Component
Isolation of Novel Sesquiterpeniods and Anti-neuroinflammatory Metabolites from Nardostachys jatamansi

NEUROPROTECTIVE
Neuroprotective Natural Products for Alzheimer’s Disease

ANTIDEPRESSANT
Comparative and Functional Screening of Three Species Traditionally used as Antidepressants: Valeriana officinalis L., Valeriana jatamansi Jones ex Roxb. and Nardostachys jatamansi (D.Don) DC.
Anti depressant activity of Mamsyadi Kwatha: An Ayurvedic compound formulation

LEARNING, MEMORY, COGNITION
Nardostachys jatamansi extract prevents chronic restraint stress-induced learning and memory deficits in a radial arm maze task
In Vitro Screening for Anti-Cholinesterase and Antioxidant Activity of Methanolic Extracts of Ayurvedic Medicinal Plants Used for Cognitive Disorders
Investigation of Neuropsychopharmacological Effects of a Polyherbal Formulation on the Learning and Memory Process in Rats
Herbal drugs and natural bioactive products as potential therapeutics: A review on pro-cognitives and brain boosters perspectives

ALZHEIMER’S DISEASE
Therapeutic Potential of Phytoconstituents in Management of Alzheimer’s Disease
Neuroprotective Natural Products for Alzheimer’s Disease
Ayurvedic medicinal plants for Alzheimer’s disease: a review
Phyto-Therapeutic and Nanomedicinal Approaches to Cure Alzheimer’s Disease: Present Status and Future Opportunities
Indian Medicinal Herbs and Formulations for Alzheimer’s Disease, from Traditional Knowledge to Scientific Assessment
INSOMNIA
A comparative clinical study on the effect of Tagara (Valeriana wallichii DC.) and Jatamansi (Nardostachys jatamansi DC.) in the management of Anidra (primary insomnia)

PARKINSON’S DISEASE
Nardosinone Alleviates Parkinson’s Disease Symptoms in Mice by Regulating Dopamine D2 Receptor
Natural products: a hope for glioblastoma patients

EPILEPSY
Is There Any Scientific Basis of Hawan to be used in Epilepsy-Prevention/Cure?

CATALEPSY
Reversal of reserpine-induced orofacial dyskinesia and catalepsy by Nardostachys jatamansi
Evaluation of toxicological and antioxidant potential of Nardostachys jatamansi in reversing haloperidol-induced catalepsy in rats

GASTRIC ULCER
Protective Effect of a Polyherbal Traditional Formula Consisting of Rosa damascena Mill., Glycyrrhiza glabra L. And Nardostachys jatamansi DC., Against Ethanol-induced Gastric Ulcer

ACUTE PANCREATITIS
Effect of biologically active fraction of Nardostachys jatamansi on cerulein-induced acute pancreatitis
Nardostachys jatamansi inhibits severe acute pancreatitis via mitogen-activated protein kinases

CANCER
BREAST
Evaluation of antioxidant and anticancer activity of extract and fractions of Nardostachys jatamansi DC in breast carcinoma
GLIOBLASTOMA
Natural products: a hope for glioblastoma patients
Review of Natural Product-Derived Compounds as Potent Antiglioblastoma Drugs
NEUROBLASTOMA
Nardostachys jatamansi Root Extract Modulates the Growth of IMR-32 and SK-N-MC Neuroblastoma Cell Lines Through MYCN Mediated Regulation of MDM2 and p53

USE WITH CHEMOTHERAPY
Effect of Nardostachys jatamansi DC. on Apoptosis, Inflammation and Oxidative Stress Induced by Doxorubicin in Wistar Rats

RADIOPROTECTIVE
Protective Effect of Nardostachys jatamansi Against Radiation-induced Damage at Biochemical and Chromosomal Levels in Swiss Albino Mice
The Efficacy of Nardostachys Jatamansi Against The Radiation Induced Haematological Damage In Rats

DIABETES
Nardostachys jatamansi extract protects against cytokine-induced β-cell damage and streptozotocin-induced diabetes
Plant Extracts for Type 2 Diabetes: From Traditional Medicine to Modern Drug Discovery

PROMOTES HAIR GROWTH
Phytochemical investigation and hair growth studies on the rhizomes of Nardostachys jatamansi DC