Ma Xing Shi Gan Tang 麻杏石甘汤
Ephedra, Apricot kernel, Gypsum and Licorice Decoction
TCM
Discussion of Cold Induced Disorders (Shang Han Lun) C.220
Decoct the Gypsum for 45 minutes before adding the other ingredients.
Opens the Lungs, moves Lung Qi, clears Heat, stops Cough and Wheezing
Fever (with or without sweating), thirst, cough, wheezing, yellow tongue coat, with a rapid pulse
1. Upper Respiratory Tract Infection
2. Bronchial Asthma
3. Pneumonia (lobar or bronchial
4. Bronchiolitis
5. Whooping Cough
6. Diphtheria
The above is taken over the course of the day in 3 equal doses.
Not used for Wheezing from Cold or Deficiency
1. When Apricot kernels are omitted and Fresh Ginger and Chinese Red Dates Da Zao are added it is called Yue Bi Tang (Maidservant from Yue Decoction). Used for Wind- edema, a generalised Edema beginning in the face with slight Fever, aversion to drafts, continuous sweating and a floating (superficial) pulse. Doses are Ma Huang 9 grams, fresh Ginger 9 grams, Gypsum 18 grams, Red Dates 5 pieces and Licorice 5 grams. Used for acute Nephritis, Edema due to Nephritis, Hydrocele and has been used for Rheumatoid Arthritis.
2. When Atracylodes Bai Zhu is added to the above, it forms Maidservant from Yue Decoction plus Atracylodes. It is used for the same purpose but with more severe deficiency.
COMPOSITION:
–[Studies on factors influencing on ephedrine contents in Maxing Shigan decoction].
–[Determination of contents of amygdalin in traditional and granular decoctions of Maxingshigan decoction by HPLC].
–[Comparison of two extraction methods for maxingshigan decoction].
–Interactions Between Ephedra sinica and Prunus armeniaca: From Stereoselectivity to Deamination as a Metabolic Detoxification Mechanism of Amygdalin.
INFLUENZA
–Inhibiting virus replication and excessive inflammatory response: Mechanism of combined prescription of Ma-Xing-Shi-Gan decoction and Xiao-Chai-Hu decoction against influenza virus.
–Mechanism by which ma-xing-shi-gan-tang inhibits the entry of influenza virus.
–Oseltamivir compared with the Chinese traditional therapy maxingshigan-yinqiaosan in the treatment of H1N1 influenza: a randomized trial.
COVID:
–Potential effect of Maxing Shigan decoction against coronavirus disease 2019 (COVID-19) revealed by network pharmacology and experimental verification.
–Potential of herbal products in prevention and treatment of COVID-19. Literature review.
–Prospective: Evolution of Chinese Medicine to Treat COVID-19 Patients in China.
–Therapeutic effects of traditional Chinese medicine (Maxingshigan-Weijing Decoction) on COVID-19: An open-label randomized controlled trial.
–Efficacy of Traditional Chinese Medicine, Maxingshigan-Weijing in the management of COVID-19 patients with severe acute respiratory syndrome: A structured summary of a study protocol for a randomized controlled trial.
–Maxingshigan decoction for treating COVID-19: A protocol for systematic review and meta analysis.
–Chemical composition and pharmacological mechanism of Qingfei Paidu Decoction and Ma Xing Shi Gan Decoction against Coronavirus Disease 2019 (COVID-19): In silico and experimental study.
–Application of Jiawei Maxing Shigan Tang in the treatment of COVID-19: An observational study.
–[Analysis of prescription and medication rules of traditional Chinese medicine in the treatment of the coronavirus disease 2019 based on traditional Chinese medicine inheritance support platform].
ASTHMA:
–Prescription pattern of Chinese herbal products for adult-onset asthma in Taiwan: a population-based study.
–The effect of Ma-Xin-Gan-Shi decoction on asthma exacerbated by respiratory syncytial virus through regulating TRPV1 channel.
–Herb pair of Ephedrae Herba-Armeniacae Semen Amarum alleviates airway injury in asthmatic rats.
–Prescription pattern of Chinese herbal products for adult-onset asthma in Taiwan: a population-based study.
PNEUMONIA:
–The rational dose for MaXingShiGan decoction is crucial for its clinical effectiveness in treating bronchial pneumonia: three randomized, double-blind, dose-parallel controlled clinical studies.
–A randomized, double-blind, placebo-controlled, multicenter clinical trial for efficacy and safety of traditional Chinese medicine combined with antibiotics in the treatment of bacterial pneumonia in children.
–[Literature study on prevention and treatment of community acquired pneumonia by traditional Chinese medicine].
–Pharmacokinetics of Maxing Shigan decoction in normal rats and RSV pneumonia model rats by HPLC-MS/MS.
CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD):
–Efficacy and safety of Maxing Shigan Decoction in the treatment of chronic obstructive pulmonary disease: A protocol for a systematic review and meta-analysis.
–Comparative effectiveness of six Chinese herb formulas for acute exacerbation of chronic obstructive pulmonary disease: a systematic review and network meta-analysis.
–Comparative effectiveness of six Chinese herb formulas for acute exacerbation of chronic obstructive pulmonary disease: protocol for systematic review and network meta-analysis.
PROTECTS FROM LUNG DAMAGE:
–Ma xing shi gan decoction eliminates PM2.5-induced lung injury by reducing pulmonary cell apoptosis through Akt/mTOR/p70S6K pathway in rats.
–Herb pair of Ephedrae Herba-Armeniacae Semen Amarum alleviates airway injury in asthmatic rats.
RADIATION INDUCED LUNG DAMAGE:
–Jiawei Maxing Shigan Tang alleviates radiation-induced lung injury via TGF-β1/Smad signaling pathway mediated by regulatory T cells.
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Ephedra, Apricot kernel, Gypsum and Licorice Decoction
Tradition:
TCM
Source / Author:
Discussion of Cold Induced Disorders (Shang Han Lun) C.220
Herb NameMa Huang (Ephedra)Shi Gao (Gypsum) Xing Ren (Apricot seed) Zhi Gan Cao (Fried Licorice) |
|
Preparation:
Decoct the Gypsum for 45 minutes before adding the other ingredients.
Function:
Opens the Lungs, moves Lung Qi, clears Heat, stops Cough and Wheezing
Use:
Fever (with or without sweating), thirst, cough, wheezing, yellow tongue coat, with a rapid pulse
1. Upper Respiratory Tract Infection
2. Bronchial Asthma
3. Pneumonia (lobar or bronchial
4. Bronchiolitis
5. Whooping Cough
6. Diphtheria
Dose:
The above is taken over the course of the day in 3 equal doses.
Cautions:
Not used for Wheezing from Cold or Deficiency
Modifications:
1. When Apricot kernels are omitted and Fresh Ginger and Chinese Red Dates Da Zao are added it is called Yue Bi Tang (Maidservant from Yue Decoction). Used for Wind- edema, a generalised Edema beginning in the face with slight Fever, aversion to drafts, continuous sweating and a floating (superficial) pulse. Doses are Ma Huang 9 grams, fresh Ginger 9 grams, Gypsum 18 grams, Red Dates 5 pieces and Licorice 5 grams. Used for acute Nephritis, Edema due to Nephritis, Hydrocele and has been used for Rheumatoid Arthritis.
2. When Atracylodes Bai Zhu is added to the above, it forms Maidservant from Yue Decoction plus Atracylodes. It is used for the same purpose but with more severe deficiency.
COMPOSITION:
–[Studies on factors influencing on ephedrine contents in Maxing Shigan decoction].
–[Determination of contents of amygdalin in traditional and granular decoctions of Maxingshigan decoction by HPLC].
–[Comparison of two extraction methods for maxingshigan decoction].
–Interactions Between Ephedra sinica and Prunus armeniaca: From Stereoselectivity to Deamination as a Metabolic Detoxification Mechanism of Amygdalin.
INFLUENZA
–Inhibiting virus replication and excessive inflammatory response: Mechanism of combined prescription of Ma-Xing-Shi-Gan decoction and Xiao-Chai-Hu decoction against influenza virus.
–Mechanism by which ma-xing-shi-gan-tang inhibits the entry of influenza virus.
–Oseltamivir compared with the Chinese traditional therapy maxingshigan-yinqiaosan in the treatment of H1N1 influenza: a randomized trial.
COVID:
–Potential effect of Maxing Shigan decoction against coronavirus disease 2019 (COVID-19) revealed by network pharmacology and experimental verification.
–Potential of herbal products in prevention and treatment of COVID-19. Literature review.
–Prospective: Evolution of Chinese Medicine to Treat COVID-19 Patients in China.
–Therapeutic effects of traditional Chinese medicine (Maxingshigan-Weijing Decoction) on COVID-19: An open-label randomized controlled trial.
–Efficacy of Traditional Chinese Medicine, Maxingshigan-Weijing in the management of COVID-19 patients with severe acute respiratory syndrome: A structured summary of a study protocol for a randomized controlled trial.
–Maxingshigan decoction for treating COVID-19: A protocol for systematic review and meta analysis.
–Chemical composition and pharmacological mechanism of Qingfei Paidu Decoction and Ma Xing Shi Gan Decoction against Coronavirus Disease 2019 (COVID-19): In silico and experimental study.
–Application of Jiawei Maxing Shigan Tang in the treatment of COVID-19: An observational study.
–[Analysis of prescription and medication rules of traditional Chinese medicine in the treatment of the coronavirus disease 2019 based on traditional Chinese medicine inheritance support platform].
ASTHMA:
–Prescription pattern of Chinese herbal products for adult-onset asthma in Taiwan: a population-based study.
–The effect of Ma-Xin-Gan-Shi decoction on asthma exacerbated by respiratory syncytial virus through regulating TRPV1 channel.
–Herb pair of Ephedrae Herba-Armeniacae Semen Amarum alleviates airway injury in asthmatic rats.
–Prescription pattern of Chinese herbal products for adult-onset asthma in Taiwan: a population-based study.
PNEUMONIA:
–The rational dose for MaXingShiGan decoction is crucial for its clinical effectiveness in treating bronchial pneumonia: three randomized, double-blind, dose-parallel controlled clinical studies.
–A randomized, double-blind, placebo-controlled, multicenter clinical trial for efficacy and safety of traditional Chinese medicine combined with antibiotics in the treatment of bacterial pneumonia in children.
–[Literature study on prevention and treatment of community acquired pneumonia by traditional Chinese medicine].
–Pharmacokinetics of Maxing Shigan decoction in normal rats and RSV pneumonia model rats by HPLC-MS/MS.
CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD):
–Efficacy and safety of Maxing Shigan Decoction in the treatment of chronic obstructive pulmonary disease: A protocol for a systematic review and meta-analysis.
–Comparative effectiveness of six Chinese herb formulas for acute exacerbation of chronic obstructive pulmonary disease: a systematic review and network meta-analysis.
–Comparative effectiveness of six Chinese herb formulas for acute exacerbation of chronic obstructive pulmonary disease: protocol for systematic review and network meta-analysis.
PROTECTS FROM LUNG DAMAGE:
–Ma xing shi gan decoction eliminates PM2.5-induced lung injury by reducing pulmonary cell apoptosis through Akt/mTOR/p70S6K pathway in rats.
–Herb pair of Ephedrae Herba-Armeniacae Semen Amarum alleviates airway injury in asthmatic rats.
RADIATION INDUCED LUNG DAMAGE:
–Jiawei Maxing Shigan Tang alleviates radiation-induced lung injury via TGF-β1/Smad signaling pathway mediated by regulatory T cells.
Back to DECOCTIONS
Back to FORMULAS
How to Modify a Formula
Substitutes
Weights & Measures