Headache and Migraine



Classical Classification of Headache:
  • Cephalgia–pain over the whole head; sometimes violent, other times mild; either acute or chronic
  • Cephalea–intolerable headache; weakens the head and senses; has paroxysms; violent pain, tinnitus, pulsing of the forehead veins, sight and hearing affected.
  • Hemicrana–one-sided headache; similar to the preceding (Galen and others treated them as one)
  • Congelatio–headache from cold numbness; originates in the rear of the head and takes away sense and feeling (similar to Lethargy or Stupor)


Now the substances which fill the head easily are those which have in their compositions an abundance of hot and vaporous Wind, or a superfluity of the Bile which is collected in the mouth of the belly. And those pains which arise through this wind are protracted“. (Syrian Book of Medicine)

The above gives a clear explanation of the idea of Wind and Bile being 2 primary causes of Headache (in this case, one-sided Headache. This concept agrees very well with TCM.

Causes of Headache
Headaches were long recognised to have numerous causes: the Heat of the Sun, bathing, change of air, wind, strong scent of spices, the smell of wine, drunkenness, stinking meat, garlic, onions, mustard, strokes, blows, bruising or great motions of the mind (excess thinking or emotions), sleep straight after dinner, excess bleeding; worms in the ears, nostrils, or stomach; choler (bile) in the stomach, repletion of the Stomach, immoderate or unnatural mixture of humors, and various other causes. (Wirtzung)

Headaches caused by one of the 4 Humors:
  • Blood: head is hot, forehead feels heavy, eyes and face are red, full veins in the face; urine is red and fatty, the pulse is soft.
  • Bile: great heat from the nostrils, tongue is dry, insomnia, thirst, pain tends to the right side of the head.
  • Melancholy: head is cold, dull color of the face, veins are not visible, little sleep, fear and worry; pain tends to the left side of the head.
  • Phlegm: senses are heavy and dull, feels cold, sleeps long, lethargic, greatest pain at the rear of the head.

TCM Differentiation of Headaches
In TCM theory, Headaches can often be associated with Wind, in addition to another factor: for example a Heat-type Headache can be referred to as Wind-Heat, Cold-type Headache to Wind-Cold, Phlegm-type Headache to Wind-Phlegm etc. Headache may also be caused by Blood stagnation with fixed pain; by chronic deficiency where the patient is weak and the headache dull, or from Trauma (which causes Blood stagnation).

TCM differentiates between Headaches caused by External and those caused by Internal Factors. External attack of Wind-Cold or Wind-Heat (suchas the start of a Codl or Flu) can cause acute Headaches. These usually come with other symptoms of Wind attack, such as Fever, Chills, runny nose or sore throat.

External Causes
Wind-Cold–sudden onset headache, pain in the neck and into the upper back and shoulder, sensitive to cold and wind, runny nose, pale face, floating and weak pulse
Formula:
Chuan Qiong Cha Tiao San
Wind-Heat–pain with a feeling of distention, sensitive to wind, thirsty, red face and eyes, pulse floating and fast.
Formula: Yin Qiao San

Internal Causes.

Liver Heat–pain, dizziness, irritable, insomnia, bitter taste, red tongue with little yellow coat, pulse: deep, wiry and forceful.
Formula: Tian Ma Gou Teng Yin or Long Dan Xie Gan Tang
Kidney Deficiency–headache with empty feeling in the head, dizziness, lower back pain, fatigue, tinnitus, red tongue with little coat, pulse is deep and week.
Formula: Da Bu Yuan Jian or Liu Wei Di Huang Wan
Qi and Blood Deficiency–headache with dizziness, easily frighten, worse with fatigue or exertion, shortness of breath, sensitive to wind, pale face, pale tongue with thin white coat. Pulse deep and weak.
Formula: Ba Zhen Tang or Bu Zhong Yi Qi Tang
Phlegm–dull headache, foggy head, phlegm in the chest, swollen tongue with teeth mark. Tongue coat white and sticky, pulse deep and wiry or deep and slippery, slow
Formula: Ban Xia Bai Zhu Tian Ma Tang
Heart Deficiency–Headache with Insomnia, palpitations, anxiety. Maybe the spirit is unsettled from strong emotion
Formula: Tian Wang Bu Xin Dan
Blood Stasis–chronic headache with fixed location, sharp or stabbign pain; maybe Purplish tongue or tongue with spots, coat thin and white, pulse deep and thin.
Formula: Tong Qiao Huo Xie Tang or Xue Fu Zhu Yu Tang

Headache can also be divided into excess and deficient types. Excess is primarily of Heat, Cold, Wind or Phlegm, while deficiency may primarily be Blood, Qi or Yang deficiency.

Categorization according to Channel in TCM
Based on the Meridian theory, TCM classifies Headaches based on the Meridian affected.

Taiyang
This affects the Bladder Meridian and therefore is felt at the back of the neck. It often overlaps a modern medicine diagnosis of Tension Headache.
Guiding Herb–Notopterygium Qiang Huo or Saposhnikovia Fang Feng
Shaoyang
Typically throbbing headaches on the side of the Head, overlapping diagnosis with Migraines.
Guiding Herb–Bupleurum Chai Hu or Ligusticum Chuan Xiong
Yangming
Frontal Headache, felt over the sinus. It is typically seen with acute Sinusitis.
Guiding Herb–Angelica dahurica Bai Zhi or Pueraria Ge Gen
Taiyin
Heavy headache feels like there is a tight band around the head, caused by Spleen deficiency and Damp.
Guiding Herb–Atractylodes Cang Zhu
Shaoyin
Chronic headache that feels like pain deep inside the head, due to Kidney deficiency.
Guiding Herb–Asarum Xi Xin
Jueyin
Pain at the Vertex or top of the Head. It can be related to metabolic disturbances like Hypoglycemia.
Guiding Herb–Evodia Wu Zhu Yu or Ligusticum Gao Ben

Formulas most used in TCM
According to a survey of Taiwanese databases related to the treatment of Migraines, the following 10 formulas are most used in TCM (see research here):

Headaches in General

Western Tradition

Simples
1. Feverfew is a special herb for all types of Headache and Migraine
2. Betony and Vervain have both been much used for Headaches and are often combined.
3. Eating a Crow Brain was regarded as being specific for all types of Headaches including severe and obstinate headaches. (The Secrets of Alexis, 1615)

Capitis dolori–Headache
Antispasmodic Infusion
Infusion of Hiera
Betony Infusion
Potion for Headache (Galen)
Cephalic Decoction (Charras)

Syrup of Betony (Bononiense)
Tincture of Valerian
Spirit of Wine Camphorated
Cephalic Powder

Abbots Confect of Rose (Diarrhodon Abbatis) (Nicholas)
Troches of Saffron (Nicholas)
Stomach Pills (Mesue)
Pills of Mastic (Mesue)

Pills of Mujarrab (Unani)
Imperial Pills
Arabian Pills (Nicholas)
Hiera Hermetis
Hiera Logadii
Hiera Pachii
Triphala of Coriander (Itrafil Kishneez) (Unani)

Electuary of Frankincense (Diaolibanum) (Nicholas)
Oxymel of Squill
Sothira Magna Nicolai
Oil of Dill
Oil of Bay
Oil of Orris
Oil of Spikenard
Oil of Marjoram

Oil of Oregano
Oil of Rose
TCM Classification

Blood Deficiency
Bu Gan Tang
Si Wu Tang


Blood Stagnation

Xue Fu Zhu Yu Tang
Tao Hong Si Wu Tang


Liver Qi Stagnation
Xiao Yao San


Liver Heat
Dan Zhi Xiao Yao San
Long Dan Xie Gan Wan


Liver Wind-Heat
Tian Ma Gou Teng Yin
Gou Teng San (with Phlegm)


Liver Wind-Phlegm
Ban Xia Bai Zhu Tian Ma Tang
Gou Teng San (with Heat)


Qi Deficiency
Bu Zhong Yi Qi Tang


Heart Blood Deficieny
Headache with Insomnia
Tian Wan Bu Xin Dan


Yin Deficiency
Bu Gan Tang
Qi Ju Di Huang Wan
Zuo Gui Wan


Severe
Zhi Jing San

Special Formula

PLASTER FOR CHRONIC HEADACHE
    Gum Arabic
    Myrrh
    Saffron
    Euphorbium                     3 grains ea.
Powder, mix with Egg White to an ointment and apply to the Temples and Forehead. (Secrets of Alexis)

Headache from Bile or Heat

Symptoms
Head and forehead feel hot, red eyes, belching, loathesomeness, thirst, dry mouth, bitter taste; pain is pricking, sharp, more commonly on the right hand side of the head, maybe with dizziness, the body is hot, little appetite, insomnia, irritable, angry, pulse is hard and fast, urine reddish, face yellowish. Especially in hot and dry times of the year, and in young people.

Diet
Stewed Lentils, Spinach, Chicory, Purslane, Lettuce and leafy vegetables, broths, stewed Apples and Pears, broths of Veal and Hens; drinks: whey, barley water with a little Pomegranate or Lemon juice added. Avoid wine and meat.

Medicines
Barley, Four Cold seeds, Lettuce leaf and seed, Purslane, Plantain, Black Nightshade, Violet, Water Lily flower, Poppy seed, Sandalwood

Externally
1. Oxyrrhodinum (equal parts of oil of roses, rose water, and vinegar of roses). Apply soaked linen cloths across the forehead from one temple to another. If the heat is extreme Camphor should be added.
2. Egg white beaten                    1
    Rose water                               1 oz.
    Waters of Elder and Fennel  
½ oz. ea.
Add 5 small Walnuts, beaten, and a little Saffron. Mix well; lay on the forehead with wool.
3. Ointment of Roses (Mesue)
4. Infrigidans Galeni ‘Cold Cream’ (washed wax 2 oz., oil of Roses 4 oz.)
5. Ungentum Populeum


Western Tradition

Headache from Bile / Heat
Antispasmodic Infusion
Decoction for Chronic Heat-type Headache (Mesue)
Syrup of Hops
Tincture of Balm
Elixir of Camphor

Abbots Confect of Rose (Diarrhodon Abbatis) (Nicholas)
New Rose Powder (Rosata Nouvelle)
Powder of Three Sandalwoods (Diatrionsatalum)
Troches of Camphor (Nicholas)

Electuary of the Juice of Rose (Mesue)
The Count’s Night Pills (Unani)
Pills for Headache from Bile and Phlegm
Pills of Violet (Habbe Banafsha) (Unani)
Oil of Violet
Oil of Rose


Bile Conqueror (Mkhris las rnam rgyal) (Tibetan)
Red Coral 25 (Rin chen byur dmar nyer lnga)


Headache from Liver Headache
Syrup of Hops
Tincture of Balm
Powder of Rhubarb
Powder to Cool the Liver
Powder of Three Sandalwoods (Diatrionsatalum)

Bile Conqueror (Mkhris las rnam rgyal) (Tibetan)
Sandalwood 18 (Tibetan)


Extra Formulas

Decoction for Chronic Heat-type Headache
    Roman Wormwood    1 oz.
    Fumitory                       8 drams
    Raisins stoned             1 oz.
    Agrimony                     5 drams
    Bugloss flower            6 drams
    Dodder
    Endive seed
    Agaric                           3 drams
Boil in 3 lbs down to 1.5 lbs. (De Morbis Internis Curandis, Mesue, 1551)

Pills for Headache from Bile and Phlegm
    Aloes                             6 drams
    Yellow Myrobalan       4 drams
    Mastic                           3 drams
    Rose                              2 drams
    Saffron                          1 dram
Form Pills. (De Morbis Internis Curandis, Mesue, 1551)
TCM Classification

Wind Heat
acute headache, cough, sore throat, blocked nose, maybe yellowish or green or clear or white mucus, stiff neck, restless, fever, floating rapid pulse
Yin Qiao Jie Du San
Fang Feng Tong Sheng San



Liver Heat / Liver Yang Rising (Bile)
sharp, acute or pulsating headache, dizziness, irritable and angry, insomnia, red eyes, red face, bitter taste, high colored urine .
Dan Zhi Xiao Yao San (TCM)
Long Dan Xie Gan Tang

Qi Ju Di Huang Wan
Tian Ma Gou Teng Yin




Headache caused by Cold or Phlegm

Symptoms
Headache which is not extreme, feeling heavy and Cold, tiredness, sleepiness, excess saliva, runny nose with clear mucus, pale face, loss of taste. Sennertus notes that Cold headaches can be caused by cold air and cold winds, showing this category is associated with Wind-Cold Headache of TCM.

Diet
Warming and drying; roasted meats; spiced food and wine; eat a little Marmalade after food

Medicines
Nutmeg, Mace, Cinnamon, Clove, Marjoram, Rosemary, Mastic

Externally
1. Pills to Chew: Mastic 2 drams, Pepper 1 dram, Caper root-bark half dram; powder and form pills with Vinegar of Squill; hold in the mouth
2. A gargle: Mustard seed 1 oz., Pepper 3 drams, Hyssop 1 handful; seethe in red wine with a little Honey. Use as a gargle.
3. Scented balls to smell: Cinnamon, Clove, Nutmeg, Aloeswood, Marjoram 2 drams each; with a little Musk and some Mastic, form balls. Various warming aromatics can be used to smell.
4. Promoting Sneezing is very useful in Cold Phlegm type Headache; sniffing Pepper or Hellebore root was used

Western Tradition

Headache from Cold
Sage Wine
Rosemary Wine
Decoction to Warm the Head
Powder to Warm the Head (Rondeletius)

Warming Powder for the Head
Diambra
Powder of Anise (Dianisum)
Powder of Happiness (Letificans) (Galen)
Aromatic Clove Powder (Aromaticum Caryophyllat.)
Powder of Galangal Compound (Diagalanga) (Mes.)

Pills of Mujarrab (Unani)
Wonderful Confection for Cold Nerve Diseases
Oil of Rue
Oil of Marjoram



Headache from Phlegm
Tincture of Valerian
Foetid Pills Minor of Galen
Foetid Pills Major of Galen
Theriac for Pain in the Head

Antimoron (Nicholas)


To Purge
Triphala Electuary of Coriander (Itriphal Kishneez)
Pilulae Cochia
Golden Pills
Pil. Alephangine

TCM Classification

Wind Cold Attack (acute)
acute headache, aversion to wind, no sweating or mild sweating, aching muscles, runny nose with clear mucus, chills (fever low if present), stiff neck, pulse is on the surface.
Ma Huang Tang
Gui Zhi Tang
Chuan Xiong Cha Tiao San



Wind-Phlegm Obstruction
dull, heavy headache, mental fogginess, fullness in the chest, excess mucus and saliva, nausea, coughing or vomiting saliva.
Ban Xia Bai Zhu Tian Ma Tang



Headache from Wind

Symptoms
The key indication for Wind type pain is its moving and changeable nature, much like Wind itself. The pain may be tight or tearing by nature, changes place, and is aggravated by wind or draughts, as well as stress and overthinking.

Western Tradition

Antispasmodic Infusion
Decoction to Warm the Head
Cephalic Decoction (Charras)
Syrup of Betony (Pharmacopoeia Augustana)
Tincture of Rue
Cephalic Powder
Theriac for Pain in the Head
Powder of Galangal Compound (Diagalanga) (Mes)
Pills of Mujarrab (Unani)
Electuary for the Head (Lewis)
Hiera Logadii

Garuda 5 (Khyung Lnga) (Tibetan)
Pearl 25 (Mu tig nyer lnga) (Tibetan)
Red Coral 25 (Rin chen byur dmar nyer lnga)
Chinese Classification

Wind-Phlegm
Ban Xia Bai Zhu Tian Ma Tang


Wind-Heat
Ling Jiao Gou Teng Tang




Headache caused by Melancholy

Western Tradition

Chronic Headache
Tincture of St. John’s wort
Decoction of Woods
Decoction for Chronic Heat-type Headache (Mesue)
Theriac for Pain of the Head
Pills of Hiera (Habbe Ayarij) (Unani)

Pills of Violet (Habbe Banafsha) (Unani)
Arab Confect Purging Melancholy (Confectio Ham)
Hiera Logadii


Chronic Headache from Melancholy
Arab Confect Purging Melancholy (Confectio Hamech)

Arabian Pills (Nicholas)
Hiera Logadii
Triphala of Stoechas (Itrafil of Stoechas) (Unani)

From TCM

While TCM has no direct correlation with Melancholy, Melancholy types of Headache can be associated with Qi Stagnation in acute cases, with Dampness, or with Deficiency of Yin and Blood Stagnation in chronic cases.


Headache From Blood Stagnation

Headache with fixed, constant or recurrent pain; maybe with history of Trauma; insomnia, restless, poor memory, dull complexion, dark under eyes, maybe purplish lips, tongue and nail beds, choppy pulse

Western Tradition

Headache from Blood stagnation
Syrup of Betony (Bononiense)
Tincture of St. John’s wort
Tincture of Rue
Tincture of Myrrh
Cephalic Powder
Electuary of Frankincense (Diaolibanum) (Nicholas)
Supreme 25 (Bla med nyer lnga)

From TCM

Blood Stasis
Tao Hong Si Wu Tang
Tong Qiao Huo Xue Tang
Xue Fu Zhu Yu Tang
Zheng Tian Wan

Special Formula:

TINCTURE FOR HEADACHE
    Vervain
    Feverfew
    Mistletoe
    Peony
    Frankincense

PILLS FOR HEADACHE FROM BLOOD STAGNATION
    Mastic
    Saffron
    Frankincense
    Rhubarb

HEADACHE FROM OLD INJURY
    Dang Gui
    Ligusticum Chuan Xiong
    Angelica Bai Zhi
    Mistletoe (Sang Ji Sheng)
    Notoginseng San Qi
    Salvia Dan Shen
    Cyperus Xiang Fu
(The Formulas of Dr. John H.F. Shen)

HEADACHE FROM BLOOD STAGNATION
    Dang Gui
    Ligusticum Chuan Xiong
   
Paeonia Bai Shao
   
Mistletoe (Sang Ji Sheng)
    Gastrodia Tian Ma
    Safflower (Hong Hua)
   

Headache From Hangover

Western Tradition
1. Rue, Rose, Bitter Almond, beat with Vinegar and apply to the Head.
2. Wormwood, Betony, Feverfew


Other Categories of Headache from TCM

TCM recognises Headaches from acute and chronic causes. Acute are from external attack of Wind and are therefore of the same cause as Colds and Flus. Note the formulas for Acute Headache from Wind are formulas used for Cold and Flu. Chronic are from Organ or Humoral imbalance.

Acute (External) Causes

Wind Cold Attack

acute headache, aversion to wind, no sweating or mild sweating, aching muscles, runny nose with clear mucus, chills (fever low if present), stiff neck, pulse is on the surface.
Ma Huang Tang
Gui Zhi Tang
Chuan Xiong Cha Tiao San


Wind Heat
acute headache, cough, sore throat, blocked nose, maybe yellowish or green or clear or white mucus, stiff neck, restless, fever, floating rapid pulse
Yin Qiao Jie Du San
Fang Feng Tong Sheng San

Antispasmodic Infusion
Internal Causes from Deficiency

Blood Deficiency
headache, pale face, weak, feels the cold, dizziness, poor memory, palpitations, weak and low pulse, pale lips and tongue.
Bu Gan Tang
Si Wu Tang

Special Formula:
    Dang Gui
    Ligusticum Chuan Xiong
    Gastrodia Tian Ma
    Tribulus Ci Ji Li
    Lycium Gou Qi Zi
    Angelica Bai Zhi
(The Formulas of Dr. John H.F. Shen)
   

Kidney Deficiency
dull headache, head feels empty, dizziness, tinnitus, back pain, weak knees, insomnia, sallow and weak appearance, spermatorrhea
Qi Ju Di Huang Wan
Zuo Gui Wan

Migraine

Migraine is a recurring type of headache typically affecting one side of the head with light sensitivity and nausea. There is often a throbbing pain of varying severity. Some migraines are caused by hormones, certain foods, and stress. Migraine is generally differentiated and treated similarly to Headache. However, stronger medicines may be required due to the severity.

Western Tradition

Special Medicines:
Hiera Hermetis was commended for stubborn Migraine

Hemicranea conferunt–for Migraine
Infusion of Hiera
Decoction of Wormwood

Syrup of Betony (Bononiense)
Tincture of St Johns wort
Oxymel of Squill
Powder of Rosemary Compound (Dianthos) (Nich.)

Hiera Hermetis

Troches of Saffron (Nicholas)
Troches of Scammony

Pil. Cochia
Pills for Migraine (Galen)
Pills for Migraine (2) (Galen)

Pills of Mujarrab (Unani)
Pills of Violet (Habbe Banafsha) (Unani)
Electuary of Frankincense (Diaolibanum) (Nicholas)
Diacastoreum
Adrianum Nicolai (with a decoction of Sage in wine)
Mithridate
Theriac Galeni

Tincture of Mastic
Tincture of St. Johns wort
Mustard Plaster
Oil of Spikenard

Oil of Wormwood
Oil of Squill
Oil of Bay


Garuda 5 (Khyung Lnga) (Tibetan Medicine)
Red Coral 25 (Rin chen byur dmar nyer lnga)


Headache and Migraine, to Purge
Powder of Rhubarb (Fuchs)
Pil. Aggregative Greater (Mesue)
Golden Pills (Pil Aurea)
Common Pills
Imperial Pills

Hiera Hermetis
Arabian Pills
Pilulae Alhandal

Pills of Hiera Simplex
Pills of Hiera with Agaric
Pills of Mastic (Mesue)

Pills of Mujarrab (Unani)
Pill of Three Things with Rhubarb
Stomach Pills (Mesue)

Triphala of Zamani (Itrafil Zamani) (Unani)

TCM Classification

TCM treatment for Migraines is generally as for Headache categories above. Acute Migraines where there is not a history of regular Migraine attacks may be treated with the medicines as for Acute Headaches, above.

Wind-Phlegm
Ban Xia Bai Zhu Tian Ma Tang


Qi Stagnation
Xiao Yao San
Dan Zhi Xiao Yao San
Yue Ju Wan


Wind-Heat or Liver Heat
Dan Zhi Xiao Yao San
Fang Feng Tong Sheng San
Long Dan Xie Gan Tang


Blood Stagnation
Tao Hong Si Wu Tang
Xue Fu Zhu Yu Tang
Tong Qiao Huo Xue Tang


Yang Deficiency
Fu Zi Tang



Research

1. Investigation on the Chronic Tension-Type Headache from the Persian Medicine Point of View
2. Protocols for Traditional Chinese Medicine guidelines for acute primary headache
3. Acupuncture and related therapies for tension-type headache: a systematic review and network meta-analysis
4. Natural products for migraine: Data-mining analyses of Chinese Medicine classical literature
5. Progress in Traditional Chinese Medicine for the Treatment of Migraine.
6. Different Chinese patent medicine therapies for migraine: A protocol for systematic review and network meta-analysis.