Coriolus (Trametes), Yun Zhi 云芝

Turkey Tail
Yun Zhi (TCM)
Kawaratake (Japan)
Picture Bulliard, Flora Parisiensis, vol. 7 (1776-1781)

Picture Coriolus (Adam, 2016)

Botanical name:


Coriolus versicolor (syn Trametes versicolor, Boletus versicolor)

Parts used:


Dried Mushroom (sporphore)

Temperature & Taste:


Neutral, dry. Bitter

Constituents:


Copper (326 mg/kg)

Uses:


1. Clears Damp, Strengthens Qi, Benefits Immunity:
-increases Immunity
-chronic Viral Infections–Hepatitis, HPV, HIV etc
-chronic and active Hepatitis (Chinese Pharmacopoeia)
-also for Menieres disease

2. Clears Damp, Resolves Masses:
-Anti-Tumor, Anti-Cancer effects against a range of Human Cancers
-demonstrated effectiveness against Cancers of the Breast, Liver, Esophageal, Colon, Leukemia, Cervical
-increases efficacy of doxorubicin and etoposide
-significantly increases survival time of cancer patients


Dose:


Decoction: 9–30 grams
Powder: 2–6 grams daily of the Powder; 1–2 grams daily as a tonic to increase immunity; 6 grams daily for Cancer.

Comment:


It contains Anti-tumor, Anti-cancer and Immuno-stimulating Polysaccharides like various other fungii growing on wood such as Ganoderma, Phellinus, Fomes spp. etc.

Main Combinations:


Often combined with other mushrooms with similar properties such as Ganoderma, Phellinus, Poria etc. as an immune tonic and for its anti-tumor activity.

1. Enhance Immunity:
i. Coriolus, Reishi
ii. Coriolus, Astragalus
iii. Coriolus, Poria Fu Ling, Phellinus Sang Huang, Ganoderma
2. Enhance Memory, Coriolus with Gingko (see Research below)

Cautions:


None noted

Main Preparations used:



Research:

1. GENERAL:
–Mycochemical Investigation of the Turkey Tail Medicinal Mushroom Trametes versicolor (Higher Basidiomycetes): A Potential Application of the Isolated Compounds
–Medicinal Value of Turkey Tail Fungus Trametes versicolor (L.:Fr.) Pilát (Aphyllophoromycetideae). A Literature Review
–Assessment of Bioactive Compounds and Antioxidant Activity of Turkey Tail Medicinal Mushroom Trametes versicolor (Agaricomycetes)
–Medicinal Value of Turkey Tail Fungus Trametes versicolor
–STUDY ON SELENIUM ACCUMULATION IN TURKEY TAIL FUNGUS {TRAMETES VERSICOLOR)
–The Amazing Properties of Turkey Tail Mushrooms

2. ANTIOXIDANT:
–Antioxidative, antifungal, cytotoxic and antineurodegenerative activity of selected Trametes species from Serbia
–Extracellular Polysaccharopeptides from Fermented Turkey Tail Medicinal Mushroom, Trametes versicolor (Agaricomycetes), Mitigate Oxidative Stress
–A Study on the Antioxidant Effect of Coriolus Versicolor Polysaccharide in Rat Brain Tissues

3. ANTI-VIRAL:
–Polysaccharopeptide from the Turkey Tail Fungus Trametes versicolor (L.:Fr.) Pilát Inhibits Human Immunodeficiency Virus Type 1
–Shown to reduce incidence of Herpes (HSV) outbreaks.

4. ANTI-FUNGAL:
–Antioxidative, antifungal, cytotoxic and antineurodegenerative activity of selected Trametes species from Serbia

5. IMMUNE:
–The mycelium of the Trametes versicolor (Turkey tail) mushroom and its fermented substrate each show potent and complementary immune activating
–Macrophage-Stimulating Activity of Polysaccharides Extracted from Fruiting Bodies of Coriolus versicolor (Turkey Tail Mushroom)
–Immunomodulatory Properties of Coriolus versicolor: The Role of Polysaccharopeptide
–Immunomodulatory potential of polysaccharides from Coriolus versicolor against intracellular bacteria Neisseria gonorrhoeae
–Trametes versicolor Protein YZP Activates Regulatory B Lymphocytes
–The mycelium of the Trametes versicolor (Turkey tail) mushroom and its fermented substrate each show potent and complementary immune activating properties in vitro

6. ANTIMUTAGENIC:
–Assessment of Antimutagenic Action of Trametes versicolor (Turkey Tail), Inonotus obliquus (Chaga Mushroom), and Ophiocordycetps sinensis Extracts

7. CANCER:
–Trametes versicolor (Synn. Coriolus versicolor) Polysaccharides in Cancer Therapy: Targets and Efficacy
–Hepatoma Cell Growth Inhibition by Inducing Apoptosis with Polysaccharide Isolated from Turkey Tail Medicinal Mushroom, Trametes versicolor
–Immune modulation from five major mushrooms: application to integrative oncology
–Cancer risk reduction by intake of mushrooms
–A Turkey tails polysaccharide as an immunochemotherapy agent in cancer
–Coriolus Versicolor and Ganoderma Lucidum Related Natural Products as an Adjunct Therapy for Cancers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
–Purification, characterization, and antitumor activity of a novel glucan from the fruiting bodies of Coriolus Versicolor
–Coriolus versicolor extracts: relevance in cancer management
BREAST
–Trametes versicolor (turkey tail mushrooms) and the treatment of breast Cancer
–Treatment of HER2-neu-Positive Breast Cancer with Paclitaxel and Trastuzumab Supplemented with Turkey Tail Mushrooms and Community Support
–Trametes versicolor Mushroom Immune Therapy in Breast Cancer
–One study showed 100% 10 year survival in Breast Cancer patients positive for HLA B40. (Medicinal Mushrooms A Clinical Guide – 2nd Ed., Powell, 2014)
OTHER CANCERS
–Polysaccharopeptides derived from Coriolus versicolor potentiate the S-phase specific cytotoxicity of Camptothecin (CPT) on human leukemia HL-60 cells
–Effect of Coriolus Versicolor Polysaccharide-B on the Biological Characteristics of Human Esophageal Carcinoma Cell Line Eca109
–In Vitro Anti-proliferative and Anti-invasive Effect of Polysaccharide-rich Extracts from Trametes Versicolor and Grifola Frondosa in Colon Cancer Cells
–CERVICAL: In a study of Cervical cancer 3–6 grams daily with Radiotherapy showed a clearence of cancer cells in 36% (11% in controls) and a 5-year survival of 79% (48% in controls). (Medicinal Mushrooms A Clinical Guide – 2nd Ed., Powell, 2014)
–ESOPHAGEAL: an extract (PSP) was shown to significantly increase 5 year survival rates in a double-blind trial. (Medicinal Mushrooms A Clinical Guide – 2nd Ed., Powell, 2014)
–LUNG: extends 5-year survival rate by 2–4 times for all cancer stages. (Medicinal Mushrooms A Clinical Guide – 2nd Ed., Powell, 2014)

8. NEURODEGENERATION:
–Antioxidative, antifungal, cytotoxic and antineurodegenerative activity of selected Trametes species from Serbia
–The Synergistic Beneficial Effects of Ginkgo Flavonoid and Coriolus versicolor Polysaccharide for Memory Improvements in a Mouse Model of Dementia

9. OTHER:
–Nutritional Mushroom Treatment in Meniere’s Disease with Coriolus versicolor: A Rationale for Therapeutic Intervention in Neuroinflammation and Antineurodegeneration
–Beneficial effects of a Coriolus versicolor-based vaginal gel on cervical epithelization, vaginal microbiota and vaginal health: a pilot study in asymptomatic women