Bu Zhong Yi Qi Tang 补中益气汤
Tonify Center and Increase Qi Decoction
Hochu ekki to (Japanese)
Bo jun gik gi tang (Korean)

Tradition:


TCM

Source / Author:


Clarifying Doubts about Damage from Internal and External Cause, 1247

Herb Name

Huang Qi (Astragalus)
Ren Shen
(Ginseng)
Bai Zhu
(White Atractylodes)
Zhi Gan Cao (Fried Licorice)
Dang Gui
(Chinese angelica)
Chen Pi
(Tangerine peel)
Sheng Ma
(Cimicifuga)
Chai Hu
(Bupleurum)

Latin


Astragalus membranaceus
Panax ginseng
Atractylodes macrocephala
Glycyrrhiza uralensis 
Angelica sinensis

Citrus reticulata
Cimicifuga heracleifolia
Bupleurum chinense

Amount


9–18 grms
6–12 grams
9–12 grams
3–6 grams
6–12 grams
6–9 grams
3–6 grams
3–9 grams


Preparation:


Traditionally a coarse powder was formed and a heaped teaspoonful was boiled in 2 bowls of water down to one bowl to be taken between meals.
Also commonly used in Pill or Powder form.


Function:


Tonifies Qi, strengthens Spleen and Stomach, raises Yang Qi

Use:


Spontaneous Sweating, aversion to Cold, weakness, fatigue, short of breath, pale tongue with a thin white coat with a weak or ‘flooding’ and weak pulse
1. Idiopathic Fever
2. Crohn’s diseases, Ulcerative Colitis, Celiac Disease
3. Chronic Hepatitis, Chronic Gastritis, Chronic Colitis, Chronic Nephritis
4. Hemorrhoids, Hiatus Hernia
5. Hypoglycemia
6. Chronic Fatigue Syndrome, Post Viral Syndrome
7. Poor Immunity, Leukopenia
8. Multiple Sclerosis
9. Frailty after severe or prolonged diseases, Convalescence
10. Postpartum de
ficiency (including insufficient lactation, urinary incontinence, continued spotting)
11. Hypotension
12. Functional Uterine Bleeding
13. Pernicious Anemia
14. Bladder, Colon or Uterine Prolapse

15. Useful in Cancer treatment and during Chemo-or Radio-therapy.
16. Hashimoto’s Thyroiditis

Dose:


The above can be taken in 2 doses over the course of the day.
In powdered form, 6–9 grams 2 or 3 times daily with fresh Ginger tea


Cautions:


Not used in Deficient Heat conditions, or Yin deficient Fever.

Modifications:


1. Usually a double amount of Codonopsis Dang Shen replaces Ginseng.
2. If there is more pronounced Coldness or Yang de
ficiency, add Cinnamon (Rou Gui)
3. More pronounced Dampness, add Poria Fu Ling and Amomum Sha Ren
4. Severe Pain, add Asarum
Xi Xin
5. Diarrhea, add Costus Mu Xiang
6. Ulcerative Colitis, add Pueraria Ge Gen, Poria Fu Ling, Amomum Sha Ren, Immature Orange (Zhi Shi)
7. Fluid retention, take with Wu Ling San
8. Abdominal distention and pain, add Costus and Amomum
Sha Ren
9. Fibromyalgia, take with
Shen Tong Zhu Yu Tang
10. Hashimoto’s Thyroiditis with Nodules, add Self Heal (Xia Ku Cao), Figwort (Xuan Shen), Oyster shell (Mu Li), Pinellia Ban Xia, Kelp (Kun Bu)
11. Prostatitis add Alpinia oxyphylla Yi Zhi Ren, Dodder seed (Tu Si Zi)
12. Chronic Hepatitie, add Artemisia Yin Chen Hao, Gardenia Zhi Zi,, Codonopsis Dang Shen, Poria Fu Ling
13. Weakness during Pregnancy with spotting, add Doney Hide gelatin (E Jiao), Mugwort (Ai Ye)

This can be used for many diseases associated with deficiency.
ANTI-VIRAL:
Hochu-ekki-to inhibits rhinovirus infection in human tracheal epithelial cells

COVID:
Basic pharmacological mechanisms and clinical evidence of the efficacy of hochuekkito against infectious diseases and its potential for use against COVID‐19

IMMUNOMODULATORY:
Immune-Modulatory Effects of Bu-Zhong-Yi-Qi-Tang in Ovalbumin-Induced Murine Model of Allergic Asthma
Integrating network pharmacology and experimental verification to decipher the immunomodulatory effect of Bu-Zhong-Yi-Qi-Tang against poly (I:C)-induced pulmonary inflammation

INDIGESTION:
Effects of Bu-Zhong-Yi-Qi-Tang for the treatment of functional dyspepsia: a feasibility study protocol

PULMONARY INFLAMMATION:
Integrating network pharmacology and experimental verification to decipher the immunomodulatory effect of Bu-Zhong-Yi-Qi-Tang against poly (I:C)-induced pulmonary inflammation
Differential Regulation of NF-κB and Nrf2 by Bojungikki-Tang Is Associated with Suppressing Lung Inflammation

ALLERGIC RHINITIS:
Modulation of immune tolerance with a Chinese traditional prescription inhibits allergic rhinitis in mice
Efficacy and Safety of Bojungikgi-Tang for Persistent Allergic Rhinitis: A Study Protocol for a Randomized, Double-Blind, Placebo-Controlled, Phase II Trial

ALLERGIC ASTHMA:
Immune-Modulatory Effects of Bu-Zhong-Yi-Qi-Tang in Ovalbumin-Induced Murine Model of Allergic Asthma

ATOPIC DERMATITIS:
The herbal drug, Bu-Zhong-Yi-Qi-Tang, for the treatment of atopic dermatitis: Protocol for a systematic review

HEPATOPROTECTIVE:
Kampo formula “Hochu-ekki-to” suppressed carbon tetrachloride-induced hepatotoxicity in mice

MUSCULAR ATROPHY:
The effect of Bu Zhong Yi Qi decoction on simulated weightlessness-induced muscle atrophy and its mechanisms
Kampo formula hochu-ekki-to (Bu-Zhong-Yi-Qi-Tang, TJ-41) ameliorates muscle atrophy by modulating atrogenes and AMPK in vivo and in vitro

OVERACTIVE BLADDER:
Medicinal plants and natural products for treating overactive bladder

POLYCYSTIC OVARIAN SYNDROME (PCOS)
Hochu-ekki-to Treatment Improves Reproductive and Immune Modulation in the Stress-Induced Rat Model of Polycystic Ovarian Syndrome

NEUROPROTECTIVE:
Bojungikgi-Tang, a Traditional Herbal Formula, Exerts Neuroprotective Effects and Ameliorates Memory Impairments in Alzheimer’s Disease-Like Experimental Models

ALZHEIMER’S DISEASE:
Bojungikgi-Tang, a Traditional Herbal Formula, Exerts Neuroprotective Effects and Ameliorates Memory Impairments in Alzheimer’s Disease-Like Experimental Models

CANCER:
ESOPHAGEAL:
Medicinal plants and natural products for treating overactive bladder
GASTRIC:
Effects of Chinese herbal medicine in combination with mitomycin C on gastric cancer cells
OVARIAN:
Integrated Chinese Herbal Medicine Therapy Improves the Survival of Patients With Ovarian Cancer

ENHANCES CHEMOTHERAPY:
Bu-Zhong-Yi-Qi Decoction, the Water Extract of Chinese Traditional Herbal Medicine, Enhances Cisplatin Cytotoxicity in A549/DDP Cells through Induction of Apoptosis and Autophagy
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