Anthocephalus, Kadamba

Wild Cinchona
Kadamba (Ayurveda)
Venkadambu (Siddha)
Anthocephalus cadamba
P.W. Korthals, Kruidkunde [Verhandelingen over de natuurlijke geschiedenis
der Nederlandsche overzeesche bezittingen; deel Botanie], (1839-1842)

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Botanical name:

Anthocephalus cadamba (syn. A. indicus, A. chinensis, A. morindaefolius, Neolamarckia cadamba, Nauclea cadamba, Sarcocephalus cadamba)

Parts used:

Stem-bark; also fruits and flowers

Temperature & Taste:

Cool. Sweet, Salty, Pungent

Uses:

1. Clears Heat, Resists Poison:
-Fever; Fever with Thirst
-Cough
-Burning syndrome
-poisonous Insect bites

2. Clears Heat, Stops Bleeding:
-Bleeding from Heat
-Diarrhea and Dysentery with Bleeding
-Hemoptysis

3. Clears Damp, Settles Wind:
-Rheumatism
-Tinnitus
-Numbness and Tingling

4. Astringes the Essence:
-Leukorrhea, Spermatorrhea
-Aphrodisiac
-Premature ejaculation (semen retentive)
-female diseases
-Diabetes (hypoglycemic)

5. Promotes Milk:
-used to nourish and promote Milk

6. Externally:
-leaf paste is applied to Tumors
-topically to Ulcers
-leaves are used as a gargle for sore throat

Dose:

Stem-bark Powder: 500–1500 mg (API); other sources have given much larger doses (up to 12 grams).
Decoction (1 in 10): 1–2 fluid ounces

Substitute:

1. Mitragyna parvifolia

Main Combinations:

1. Diabetes: Anthocephalus, Shorea robusta, Terminalia arjuna, Carium copticum

Major Formulas:

Nyagrodhadi Kwath Churna
Nyagrodhradi Churna
Grahnimihira Taila

Cautions:

None noted

Main Preparations used:

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1. ANTIBACTERIAL: –In Vitro antibacterial efficacy of 21 Indian timber-yielding plants against multidrug-resistant bacteria causing urinary tract infection. –Antimicrobial, wound healing and antioxidant activities of Anthocephalus cadamba. 2. ANTIOXIDANT: –Antioxidant, Antigenotoxic and Cytotoxic Activity of Anthocephalus cadamba (Roxb.) Miq. Bark Fractions and their Phytochemical Analysis using UPLC-ESI-QTOF-MS. –Antioxidant activity and identification of bioactive compounds from leaves of Anthocephalus cadamba by ultra-performance liquid chromatography/electrospray ionization quadrupole time of flight mass spectrometry. –Antimicrobial, wound healing and antioxidant activities of Anthocephalus cadamba. 3. SEDATIVE: –Sedative and antiepileptic effects of Anthocephalus cadamba Roxb. in mice and rats.

4. CYTOTOXIC: –Antioxidant, Antigenotoxic and Cytotoxic Activity of Anthocephalus cadamba (Roxb.) Miq. Bark Fractions and their Phytochemical Analysis using UPLC-ESI-QTOF-MS. 5. CANCER: –Bio-assay Guided Isolation of Anti-cancer Compounds from Anthocephalus cadamba CERVICAL CANCER: –Anthocephalus Cadamba antiproliferative effect against Human Cervical Cancer EHRLICH ASCITES CANCER –Methanolic extract of Anthocephalus cadamba induces apoptosis in Ehrlich ascites carcinoma cells in experimental mice. –Evaluation of antitumor activity and in vivo antioxidant status of Anthocephalus cadamba on Ehrlich ascites carcinoma treated mice. LYMPHOMA: –Antiproliferative Activity and Apoptosis Inducing Mechanism of Anthocephalus cadamba on Dalton’s Lymphoma Ascites Cells.